[HTML][HTML] Chemical strategies to engineer hydrogels for cell culture
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …
[HTML][HTML] Biomimetic peptide self-assembly for functional materials
Natural biomolecular systems have evolved to form a rich variety of supramolecular
materials and machinery fundamental to cellular function. The assembly of these structures …
materials and machinery fundamental to cellular function. The assembly of these structures …
Peptide design and self-assembly into targeted nanostructure and functional materials
Peptides have been extensively utilized to construct nanomaterials that display targeted
structure through hierarchical assembly. The self-assembly of both rationally designed …
structure through hierarchical assembly. The self-assembly of both rationally designed …
Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning
SA Langhans - Frontiers in pharmacology, 2018 - frontiersin.org
Drug development is a lengthy and costly process that proceeds through several stages
from target identification to lead discovery and optimization, preclinical validation and …
from target identification to lead discovery and optimization, preclinical validation and …
Self-assembled peptide and protein nanostructures for anti-cancer therapy: Targeted delivery, stimuli-responsive devices and immunotherapy
Self-assembled peptides and proteins possess tremendous potential as targeted drug
delivery systems and key applications of these well-defined nanostructures reside in anti …
delivery systems and key applications of these well-defined nanostructures reside in anti …
Personal perspective on understanding low molecular weight gels
DJ Adams - Journal of the American Chemical Society, 2022 - ACS Publications
Low molecular weight gels are formed by the self-assembly of small molecules into
anisotropic structures that form a network capable of immobilizing the solvent. Such gels are …
anisotropic structures that form a network capable of immobilizing the solvent. Such gels are …
[HTML][HTML] Designing hydrogels for controlled drug delivery
Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery
and have found clinical use. Hydrogels can provide spatial and temporal control over the …
and have found clinical use. Hydrogels can provide spatial and temporal control over the …
Supramolecular hydrogelators and hydrogels: from soft matter to molecular biomaterials
In this review we intend to provide a relatively comprehensive summary of the work of
supramolecular hydrogelators after 2004 and to put emphasis particularly on the …
supramolecular hydrogelators after 2004 and to put emphasis particularly on the …
[HTML][HTML] Supramolecular biomaterials
Polymers, ceramics and metals have historically dominated the application of materials in
medicine. Yet rationally designed materials that exploit specific, directional, tunable and …
medicine. Yet rationally designed materials that exploit specific, directional, tunable and …
[HTML][HTML] Design and applications of man-made biomimetic fibrillar hydrogels
E Prince, E Kumacheva - Nature Reviews Materials, 2019 - nature.com
Many extracellular matrices (ECMs) have a filamentous architecture, which influences cell
growth and phenotype and imparts tissues with specific properties. Man-made fibrillar …
growth and phenotype and imparts tissues with specific properties. Man-made fibrillar …