Autophagy, an essential cellular process that mediates degradation of proteins and
organelles in lysosomes, has been tightly linked to cellular quality control for its role as part …

Aging involves the systemic deterioration of all known cell types in most eukaryotes. Several
recently discovered compounds that extend the healthspan and lifespan of model organisms …

The human diet and dietary patterns are closely linked to the health status. High-calorie
Western-style diets have increasingly come under scrutiny as their caloric load and …

High incidences of morbidity and mortality associated with age-related diseases among the
elderly population are a socio-economic challenge. Aging is an irreversible and inevitable …

Accumulating evidence indicate that astrocytes are essential players of the excitatory and
inhibitory signaling during normal and epileptiform activity via uptake and release of …

With an increasing aging population, the burden of age-related diseases magnifies. To
alleviate this burden, geroprotection has been an area of intense research focus with the …

Neurodegenerative disorders are diseases characterized by progressive degeneration of
neurons and associated structures and are a major global issue growing more widespread …

Polyamines (PAs) are important molecules that determine cell longevity or death. Studies
have shown that nutritional supplementation with spermidine can reduce age-related …

Ovarian aging and disease-related decline in fertility are challenging medical and economic
issues with an increasing prevalence. Polyamines are a class of polycationic alkylamines …

Aging has emerged at the forefront of scientific research due to the growing social and
economic costs associated with the growing aging global population. The defining features …