Functional nucleic acid sensors
Sensors are devices that respond to physical or chemical stimuli and produce detectable
signals. 1r4 They are a critical extension of human perception of the world in many aspects …
signals. 1r4 They are a critical extension of human perception of the world in many aspects …
Biologically active molecules with a “light switch”
Biologically active compounds which are light‐responsive offer experimental possibilities
which are otherwise very difficult to achieve. Since light can be manipulated very precisely …
which are otherwise very difficult to achieve. Since light can be manipulated very precisely …
Functional aptamers and aptazymes in biotechnology, diagnostics, and therapy
Aptamers are single-stranded nucleic acid molecules that possess properties comparable to
those of protein monoclonal antibodies, and thus are clear alternatives to long established …
those of protein monoclonal antibodies, and thus are clear alternatives to long established …
Nucleic acid aptamers: an emerging tool for biotechnology and biomedical sensing
Detection of small molecules or proteins of living cells provides an exceptional opportunity to
study genetic variations and functions, cellular behaviors, and various diseases including …
study genetic variations and functions, cellular behaviors, and various diseases including …
Natural and engineered nucleic acids as tools to explore biology
RR Breaker - Nature, 2004 - nature.com
RNA and DNA molecules can form complex, three-dimensional folded structures that have
surprisingly sophisticated functions, including catalysing chemical reactions and controlling …
surprisingly sophisticated functions, including catalysing chemical reactions and controlling …
Fluorescence-activated cell sorting for aptamer SELEX with cell mixtures
Aptamers that target a specific cell subpopulation within composite mixtures represent
invaluable tools in biomedical research and in the development of cell-specific therapeutics …
invaluable tools in biomedical research and in the development of cell-specific therapeutics …
[PDF][PDF] Enrichment of cell‐targeting and population‐specific aptamers by fluorescence‐activated cell sorting
The reliable targeting of distinct cells and defined subpopulations of cells is an important
task in chemical biology and medicine. Therefore, sophisticated reagents are required that …
task in chemical biology and medicine. Therefore, sophisticated reagents are required that …
Single-molecule transition-state analysis of RNA folding
How RNA molecules fold into functional structures is a problem of great significance given
the expanding list of essential cellular RNA enzymes and the increasing number of …
the expanding list of essential cellular RNA enzymes and the increasing number of …
Nucleic acid aptamers as tools and drugs: recent developments
M Rimmele - Chembiochem, 2003 - Wiley Online Library
Nucleic acid aptamers are molecules that bind to their ligands with high affinity and
specificity. Unlike other functional nucleic acids such as antisense oligonucleotides …
specificity. Unlike other functional nucleic acids such as antisense oligonucleotides …
Biologisch aktive Moleküle mit “Lichtschalter”
Biologisch aktive Verbindungen, die auf Licht reagieren, bieten experimentelle
Möglichkeiten, die sonst nur sehr schwierig zu realisieren sind. Da Licht z. B. mit Lasern und …
Möglichkeiten, die sonst nur sehr schwierig zu realisieren sind. Da Licht z. B. mit Lasern und …