Antibiotic resistance in the patient with cancer: Escalating challenges and paths forward
AK Nanayakkara, HW Boucher… - CA: a cancer journal …, 2021 - Wiley Online Library
Infection is the second leading cause of death in patients with cancer. Loss of efficacy in
antibiotics due to antibiotic resistance in bacteria is an urgent threat against the continuing …
antibiotics due to antibiotic resistance in bacteria is an urgent threat against the continuing …
The IS6 family, a clinically important group of insertion sequences including IS26
The IS 6 family of bacterial and archaeal insertion sequences, first identified in the early
1980s, has proved to be instrumental in the rearrangement and spread of multiple antibiotic …
1980s, has proved to be instrumental in the rearrangement and spread of multiple antibiotic …
[HTML][HTML] Perspectives on systematic generation of antibiotic resistance with special emphasis on modern antibiotics
IK Kavya, N Kochhar, A Ghosh, S Shrivastava… - Total Environment …, 2023 - Elsevier
Antibiotics, considered a “wonder medication” in the 20th century, have been exploited to
such an extent that bacteria have developed resistance against them giving rise to highly …
such an extent that bacteria have developed resistance against them giving rise to highly …
Within-host evolution of bacterial pathogens in acute and chronic infection
JP Dekker - Annual Review of Pathology: Mechanisms of …, 2024 - annualreviews.org
Bacterial pathogens undergo remarkable adaptive change in response to the selective
forces they encounter during host colonization and infection. Studies performed over the …
forces they encounter during host colonization and infection. Studies performed over the …
Plasmids Shape the Current Prevalence of tmexCD1-toprJ1 among Klebsiella pneumoniae in Food Production Chains
The emergence of novel antimicrobial resistance genes conferring resistance to last-resort
antimicrobials poses a serious challenge to global public health security. Recently, one …
antimicrobials poses a serious challenge to global public health security. Recently, one …
IS26 and the IS26 family: versatile resistance gene movers and genome reorganizers
In Gram-negative bacteria, the insertion sequence IS 26 is highly active in disseminating
antibiotic resistance genes. IS 26 can recruit a gene or group of genes into the mobile gene …
antibiotic resistance genes. IS 26 can recruit a gene or group of genes into the mobile gene …
Comprehensive Genomic Investigation of Tigecycline Resistance Gene tet(X4)-Bearing Strains Expanding among Different Settings
R Li, Y Li, K Peng, Y Yin, Y Liu, T He, L Bai… - Microbiology …, 2021 - Am Soc Microbiol
The emergence of plasmid-mediated tigecycline resistance genes has attracted a great deal
of attention globally. Currently, no comprehensive in-depth genomic epidemiology study of …
of attention globally. Currently, no comprehensive in-depth genomic epidemiology study of …
Mechanisms of IS26-Mediated Amplification of the aphA1 Gene Leading to Tobramycin Resistance in an Acinetobacter baumannii Isolate
CJ Harmer, F Lebreton, J Stam, PT McGann… - Microbiology …, 2022 - Am Soc Microbiol
Enhanced levels of resistance to antibiotics arising from amplification of an antibiotic
resistance gene that impact therapeutic options are increasingly observed. Amplification can …
resistance gene that impact therapeutic options are increasingly observed. Amplification can …
Transiently silent acquired antimicrobial resistance: an emerging challenge in susceptibility testing
Acquisition and expression of antimicrobial resistance (AMR) mechanisms in bacteria are
often associated with a fitness cost. Thus, evolutionary adaptation and fitness cost …
often associated with a fitness cost. Thus, evolutionary adaptation and fitness cost …
Klebsiella Pneumoniae: An Update on Antibiotic Resistance Mechanisms
M Karami-Zarandi, HA Rahdar, H Esmaeili… - Future …, 2023 - Taylor & Francis
Klebsiella pneumoniae colonizes mucosal surfaces of healthy humans and is responsible
for one third of all Gram-negative infections in hospitalized patients. K. pneumoniae is …
for one third of all Gram-negative infections in hospitalized patients. K. pneumoniae is …