IFITM proteins: Understanding their diverse roles in viral infection, cancer, and immunity

M Gómez-Herranz, J Taylor, RD Sloan - Journal of Biological Chemistry, 2023 - ASBMB
Interferon-induced transmembrane proteins (IFITMs) are broad spectrum antiviral factors that
inhibit the entry of a wide range of clinically important pathogens including influenza A virus …

The impact of pathogens on sepsis prevalence and outcome

B Dyck, M Unterberg, M Adamzik, B Koos - Pathogens, 2024 - mdpi.com
Sepsis, a severe global healthcare challenge, is characterized by significant morbidity and
mortality. The 2016 redefinition by the Third International Consensus Definitions Task Force …

An RBM10 and NF-κB interacting host lncRNA promotes JEV replication and neuronal cell death

S Tripathi, S Sengar, B Shree, S Mohapatra… - Journal of …, 2023 - Am Soc Microbiol
Infection of the central nervous system by the Japanese encephalitis virus (JEV) is
characterized by extensive neuronal cell death and neuroinflammation. Several protein …

SARS-CoV-2 variant delta potently suppresses innate immune response and evades interferon-activated antiviral responses in human colon epithelial cells

D Tandel, V Sah, NK Singh, PS Potharaju… - Microbiology …, 2022 - Am Soc Microbiol
The Delta variant of SARS-CoV-2 has caused more severe infections than its previous
variants. We studied the host innate immune response to Delta, Alpha, and two earlier …

[HTML][HTML] TL-532, a novel specific Toll-like receptor 3 agonist rationally designed for targeting cancers: discovery process and biological characterization

S Thierry, S Maadadi, A Berton, L Dimier, C Perret… - Microbial Cell, 2023 - ncbi.nlm.nih.gov
Abstract Toll-like receptor 3 (TLR3) is an innate immune receptor that recognizes double-
stranded RNA (dsRNA) and induces inflammation in immune and normal cells to initiate anti …

The ceRNA network regulates epithelial-mesenchymal transition in colorectal cancer

R Li, H Xu, X Gao - Heliyon, 2023 - cell.com
Epithelial-mesenchymal transition (EMT) is a biological process that transforms epithelial
cells into a mesenchymal phenotype, conferring cell migration and invasion capabilities …

Japanese Encephalitis Virus-Infected Cells

KB Sharma, S Chhabra, M Kalia - Virus Infected Cells, 2023 - Springer
RNA virus infections have been a leading cause of pandemics. Aided by global warming
and increased connectivity, their threat is likely to increase over time. The flaviviruses are …

White spot syndrome virus achieves early infection through Snail2 suppression of Relish nuclear translocation

C Xiao-Tong, L Gang, W Lian-Jie, L Jiang-Feng - Aquaculture, 2024 - Elsevier
In vertebrates, Snails are evolutionarily conserved and consist of 4–6 Cys2-His2 (C2H2)-
Zinc finger domains. The key role of the Snails is well illustrated in cancer, but its role in …

[PDF][PDF] SARS-CoV-2 Variant Delta Potently Suppresses Innate Immune Response and Evades Interferon-Activated Antiviral Responses in Human Colon Epithelial …

KH Harshan - 2022 - researchgate.net
The Delta variant of SARS-CoV-2 has caused more severe infections than its previous
variants. We studied the host innate immune response to Delta, Alpha, and two earlier …