Design of Coiled-coil Protein Nanostructures for Therapeutics and Drug Delivery
D Britton, JW Sun, PD Renfrew… - Annual Review of …, 2024 - annualreviews.org
Coiled-coil protein motifs have become widely employed in the design of biomaterials.
Some of these designs have been studied for use in drug delivery due to the unique ability …
Some of these designs have been studied for use in drug delivery due to the unique ability …
An overview of enhancing the performance of medical implants with nanocomposites
M Ramezani, ZM Ripin - Journal of Composites Science, 2023 - mdpi.com
Medical implants are essential tools for treating chronic illnesses, restoring physical function,
and improving the quality of life for millions of patients worldwide. However, implant failures …
and improving the quality of life for millions of patients worldwide. However, implant failures …
Engineered Proteins and Materials Utilizing Residue-Specific Noncanonical Amino Acid Incorporation
T Majekodunmi, D Britton, JK Montclare - Chemical reviews, 2024 - ACS Publications
The incorporation of noncanonical amino acids into proteins and protein-based materials
has significantly expanded the repertoire of available protein structures and chemistries …
has significantly expanded the repertoire of available protein structures and chemistries …
Coiled-Coil Protein Hydrogels Engineered with Minimized Fiber Diameters for Sustained Release of Doxorubicin in Triple-Negative Breast Cancer
Triple-negative breast cancer (TNBC) lacks expressed protein targets, making therapy
development challenging. Hydrogels offer a promising new route in this regard by improving …
development challenging. Hydrogels offer a promising new route in this regard by improving …
Supramolecular Assembly and Small-Molecule Binding by Protein-Engineered Coiled-Coil Fibers
The ability to engineer a solvent-exposed surface of self-assembling coiled coils allows one
to achieve a higher-order hierarchical assembly such as nano-or microfibers. Currently …
to achieve a higher-order hierarchical assembly such as nano-or microfibers. Currently …
Protein-Engineered Fibers For Drug Encapsulation Traceable via 19F Magnetic Resonance
Theranostic materials research is experiencing rapid growth driven by the interest in
integrating both therapeutic and diagnostic modalities. These materials offer the unique …
integrating both therapeutic and diagnostic modalities. These materials offer the unique …
Dual coiled-coil protein domain mimic and drug delivery vehicle for SARS-CoV-2
SARS-CoV-2 has emerged as a strong target for the development of protein domain mimics
(PDMs) as it relies on the helical protein-protein interaction (PPI) between the N-terminal α …
(PDMs) as it relies on the helical protein-protein interaction (PPI) between the N-terminal α …
Recombinant Fibrous Protein Gels as Rheological Modifiers in Skin Ointments
Rheological modifiers are an important component in the development of skin cream (SC)
chassis for personal skin care products (PSCPs). The viscous behavior of a PSCP is critical …
chassis for personal skin care products (PSCPs). The viscous behavior of a PSCP is critical …
Strategies and Applications for Supramolecular Protein Self‐Assembly
Y Li, R Tian, Y Zou, T Wang, J Liu - Chemistry–A European Journal - Wiley Online Library
Supramolecular chemistry achieves higher‐order molecular self‐assembly through non‐
covalent interactions. Utilizing supramolecular methods to explore the polymorphism of …
covalent interactions. Utilizing supramolecular methods to explore the polymorphism of …