[HTML][HTML] Overweight and obesity in pregnancy: their impact on epigenetics

C Reichetzeder - European journal of clinical nutrition, 2021 - nature.com
Over the last few decades, the prevalence of obesity has risen to epidemic proportions
worldwide. Consequently, the number of obesity in pregnancy has risen drastically …

[HTML][HTML] Epigenetic programming and fetal metabolic programming

Z Zhu, F Cao, X Li - Frontiers in endocrinology, 2019 - frontiersin.org
Fetal metabolic programming caused by the adverse intrauterine environment can induce
metabolic syndrome in adult offspring. Adverse intrauterine environment introduces fetal …

[HTML][HTML] Maternal obesity and risk of low birth weight, fetal growth restriction, and macrosomia: multiple analyses

M Lewandowska - Nutrients, 2021 - mdpi.com
The associations between maternal pre-pregnancy obesity and low birth weight (LBW,<
2500 g) remain inconclusive. Therefore, birth weight in a Polish prospective cohort of 912 …

[HTML][HTML] Intrauterine programming of obesity and type 2 diabetes

DS Fernandez-Twinn, L Hjort, B Novakovic, SE Ozanne… - Diabetologia, 2019 - Springer
The type 2 diabetes epidemic and one of its predisposing factors, obesity, are major
influences on global health and economic burden. It is accepted that genetics and the …

[HTML][HTML] Recent progress in epigenetics of obesity

FY Wu, RX Yin - Diabetology & Metabolic Syndrome, 2022 - Springer
Nowadays, obesity is one of the largest public health problems worldwide. In the last few
decades, there has been a marked increase in the obesity epidemic and its related …

[HTML][HTML] Recent advances in the knowledge of the mechanisms of leptin physiology and actions in neurological and metabolic pathologies

ME Casado, R Collado-Pérez, LM Frago… - International Journal of …, 2023 - mdpi.com
Excess body weight is frequently associated with low-grade inflammation. Evidence
indicates a relationship between obesity and cancer, as well as with other diseases, such as …

[HTML][HTML] Prenatal psychological or metabolic stress increases the risk for psychiatric disorders: the “funnel effect” model

C Musillo, A Berry, F Cirulli - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Adverse stressful experiences in utero can redirect fetal brain development, ultimately
leading to increased risk for psychiatric disorders. Obesity during pregnancy can have …

[HTML][HTML] The complex roles of adipokines in polycystic ovary syndrome and endometriosis

S Schüler-Toprak, O Ortmann, C Buechler, O Treeck - Biomedicines, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) and endometriosis are frequent diseases of the female
reproductive tract causing high morbidity as they can significantly affect fertility and quality of …

[HTML][HTML] Transgenerational inheritance of environmentally induced epigenetic alterations during mammalian development

L Legoff, SC D'Cruz, S Tevosian, M Primig… - Cells, 2019 - mdpi.com
Genetic studies traditionally focus on DNA as the molecule that passes information on from
parents to their offspring. Changes in the DNA code alter heritable information and can more …

[HTML][HTML] Chronic stress, epigenetics, and adipose tissue metabolism in the obese state

Y Xiao, D Liu, MA Cline, ER Gilbert - Nutrition & metabolism, 2020 - Springer
In obesity, endocrine and metabolic perturbations, including those induced by chronic
activation of the hypothalamus–pituitary–adrenal axis, are associated with the accumulation …