The vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) play crucial
roles in vasculogenesis and angiogenesis. Angiogenesis is an important mechanism in …

The vascular endothelial growth factor (VEGF) family of growth factors controls pathological
angiogenesis and increased vascular permeability in important eye diseases such as …

In a cell-free approach to regenerative therapeutics, transient application of paracrine factors
in vivo could be used to alter the behavior and fate of progenitor cells to achieve sustained …

Hypertrophic chondrocytes in the epiphyseal growth plate express the angiogenic protein
vascular endothelial growth factor (VEGF). To determine the role of VEGF in endochondral …

Vascular endothelial growth factor (VEGF) is a fundamental regulator of normal and
abnormal angiogenesis. Recent evidence indicates that VEGF is essential for embryonic …

Vascular endothelial growth factor (VEGF) is a secreted mitogen highly specific for cultured
endothelial cells. In vivo VEGF induces microvascular permeability and plays a central role …

Pulmonary emphysema, a significant global health problem, is characterized by a loss of
alveolar structures. Because VEGF is a trophic factor required for the survival of endothelial …

Proof that therapeutic angiogenesis could be successfully extended to human subjects was
first demonstrated using gene transfer of naked DNA encoding for VEGF (phVEGF) for the …

Abstract Learning Objectives After completing this course, the reader will be able to: Explain
the biology of angiogenesis. Identify the role of VEGF in normal and tumor angiogenesis …

Unlike during development, blood vessels in the adult are generally thought not to require
VEGF for normal function. However, VEGF is a survival factor for many tumor vessels, and …