Identification of biomarkers for the early detection of non-small cell lung cancer: a systematic review and meta-analysis

E Mohamed, DJ García Martínez, MS Hosseini… - …, 2024 - academic.oup.com
Lung cancer (LC) causes few symptoms in the earliest stages, leading to one of the highest
mortality rates among cancers. Low-dose computerised tomography (LDCT) is used to …

Contents in tumor-educated platelets as the novel biosource for cancer diagnostics

Q Zhang, X Song, X Song - Frontiers in Oncology, 2023 - frontiersin.org
Liquid biopsy, a powerful non-invasive test, has been widely used in cancer diagnosis and
treatment. Platelets, the second most abundant cells in peripheral blood, are becoming one …

Machine-learning and scRNA-Seq-based diagnostic and prognostic models illustrating survival and therapy response of lung adenocarcinoma

Q Cheng, W Zhao, X Song, T Jin - Genes & Immunity, 2024 - nature.com
Lung cancer is a major cause accounting for cancer-related mortalities, with lung
adenocarcinoma (LUAD) being the most prevalent subtype. Given the high clinical and …

Circular RNAs: Characteristics, functions, mechanisms, and potential applications in thyroid cancer

M Wu, H Yuan, W Zou, S Xu, S Liu, Q Gao… - Clinical and …, 2024 - Springer
Thyroid cancer (TC) is one of the most common endocrine malignancies, and its incidence
has increased globally. Despite extensive research, the underlying molecular mechanisms …

Early-stage idiopathic Parkinson's disease is associated with reduced circular RNA expression

BJ Whittle, OG Izuogu, H Lowes, D Deen, A Pyle… - npj Parkinson's …, 2024 - nature.com
Neurodegeneration in Parkinson's disease (PD) precedes diagnosis by years. Early
neurodegeneration may be reflected in RNA levels and measurable as a biomarker. Here …

Application of machine learning for high-throughput tumor marker screening

X Fu, W Ma, Q Zuo, Y Qi, S Zhang, Y Zhao - Life Sciences, 2024 - Elsevier
High-throughput sequencing and multiomics technologies have allowed increasing
numbers of biomarkers to be mined and used for disease diagnosis, risk stratification …

[HTML][HTML] Liquid biopsy in detecting early non-small cell lung cancer

R Rosell, M Santarpia, C Pedraz-Valdunciel… - The Journal of Liquid …, 2023 - Elsevier
Lung cancer screening programs, particularly in the UK, have shown a decrease in lung
cancer-related deaths among individuals who underwent low-dose computed tomography …

[HTML][HTML] Discriminating Benign from Malignant Lung Diseases Using Plasma Glycosaminoglycans and Cell-Free DNA

A Qvick, S Bratulic, J Carlsson, B Stenmark… - International Journal of …, 2024 - mdpi.com
We aimed to investigate the use of free glycosaminoglycan profiles (GAGomes) and cfDNA
in plasma to differentiate between lung cancer and benign lung disease, in a cohort of 113 …

Identification of circRNA-miRNA-mRNA networks to explore underlying mechanism in lung cancer

Y Wang, Y Fu - Health Information Science and Systems, 2025 - Springer
Background Circular RNAs (circRNAs) are involved in the occurrence and development of
various tumors. CircRNAs can act as competing endogenous RNAs (ceRNAs), which are …

Plasma glycosaminoglycans and cell-free DNA to discriminate benign and malignant lung diseases

A Qvick, S Bratulic, J Carlsson, B Stenmark, C Karlsson… - medRxiv, 2024 - medrxiv.org
We aimed to investigate the use of free glycosaminoglycan profiles (GAGomes) and cfDNA
in plasma to differentiate between lung cancer and benign lung disease. GAGs were …