[HTML][HTML] Patients with COVID-19: in the dark-NETs of neutrophils
SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …
COVID-19 and respiratory system disorders: current knowledge, future clinical and translational research questions
SB Brosnahan, AH Jonkman, MC Kugler… - … , and vascular biology, 2020 - Am Heart Assoc
The severe acute respiratory syndrome coronavirus-2 emerged as a serious human
pathogen in late 2019, causing the disease coronavirus disease 2019 (COVID-19). The …
pathogen in late 2019, causing the disease coronavirus disease 2019 (COVID-19). The …
[HTML][HTML] Neutrophils in COVID-19: not innocent bystanders
E McKenna, R Wubben, JM Isaza-Correa… - Frontiers in …, 2022 - frontiersin.org
Unusually for a viral infection, the immunological phenotype of severe COVID-19 is
characterised by a depleted lymphocyte and elevated neutrophil count, with the neutrophil …
characterised by a depleted lymphocyte and elevated neutrophil count, with the neutrophil …
[HTML][HTML] Oral inhalation for delivery of proteins and peptides to the lungs
E Fröhlich, S Salar-Behzadi - European Journal of Pharmaceutics and …, 2021 - Elsevier
Oral inhalation is the preferred route for delivery of small molecules to the lungs, because
high tissue levels can be achieved shortly after application. Biologics are mainly …
high tissue levels can be achieved shortly after application. Biologics are mainly …
[HTML][HTML] Neurological consequences of COVID-19: what have we learned and where do we go from here?
Abstract The coronavirus disease-19 (COVID-19) pandemic is an unprecedented worldwide
health crisis. COVID-19 is caused by SARS-CoV-2, a highly infectious pathogen that is …
health crisis. COVID-19 is caused by SARS-CoV-2, a highly infectious pathogen that is …
[HTML][HTML] Proteome profiling of recombinant DNase therapy in reducing NETs and aiding recovery in COVID-19 patients
Severe coronavirus disease 2019 (COVID-19) can result in pneumonia and acute
respiratory failure. Accumulation of mucus in the airways is a hallmark of the disease and …
respiratory failure. Accumulation of mucus in the airways is a hallmark of the disease and …
[HTML][HTML] Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: a case series
Background Mechanically ventilated patients with COVID-19 have a mortality of 24–53%, in
part due to distal mucopurulent secretions interfering with ventilation. DNA from neutrophil …
part due to distal mucopurulent secretions interfering with ventilation. DNA from neutrophil …
Association between acute pancreatitis and COVID-19: could pancreatitis be the missing piece of the puzzle about increased mortality rates?
C Akarsu, M Karabulut, H Aydin… - Journal of …, 2022 - Taylor & Francis
Background The COVID-19 pandemic caused by SARS-CoV-2 commenced in Wuhan
China in 2019 and soon spread worldwide. SARS-CoV-2 enters the cell by binding to the …
China in 2019 and soon spread worldwide. SARS-CoV-2 enters the cell by binding to the …
[HTML][HTML] Nanomedicine strategies to target coronavirus
With the severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002, the middle
east respiratory syndrome CoV (MERS-CoV) in 2012 and the recently discovered SARS …
east respiratory syndrome CoV (MERS-CoV) in 2012 and the recently discovered SARS …
[HTML][HTML] Vasculitis and neutrophil extracellular traps in lungs of golden Syrian hamsters with SARS-CoV-2
K Becker, G Beythien, N de Buhr… - Frontiers in …, 2021 - frontiersin.org
Neutrophil extracellular traps (NETs) have been identified as one pathogenetic trigger in
severe COVID-19 cases and therefore well-described animal models to understand the …
severe COVID-19 cases and therefore well-described animal models to understand the …