Brown fat is emerging as an interesting and promising target for therapeutic intervention in
obesity and metabolic disease. Activation of brown fat in humans is associated with marked …

Thyroid hormones (TH) are crucial for development, growth, differentiation, metabolism and
thermogenesis. Skeletal muscle (SM) contractile function, myogenesis and bioenergetic …

BACKGROUND: Tissue homeostasis depends on the balance between cell proliferation and
differentiation. Thyroid hormones (THs), through binding to their nuclear receptors, can …

Background: An in-depth understanding of the fundamental principles that regulate thyroid
hormone homeostasis is critical for the development of new diagnostic and treatment …

The application of cryotherapy is widely used in sports medicine today. Cooling could
minimize secondary hypoxic injury through the reduction of cellular metabolism and injury …

Skeletal muscles are composed of several types of fibers with different contractile and
metabolic properties. Genetic background and type of innervation of the fibers primarily …

Myogenesis is controlled by an elaborate system of extrinsic and intrinsic regulatory
mechanisms in all development stages. The aim of this review is to provide an overview of …

It is known that thyroid hormone (TH) is a major determinant of muscle fiber composition, but
the molecular mechanism by which it does so remains unclear. Here, we demonstrated that …

It is well known that thyroid hormone affects body composition; however, the effect of the
thyroid hormone receptor β (TRβ)-selective thyromimetic GC-1 on this biological feature had …

Resistance to thyroid hormone (RTH), a dominantly inherited disorder usually associated
with mutations in thyroid hormone receptor β (THRB), is characterized by elevated levels of …