Keloids constitute an abnormal fibroproliferative wound healing response in which raised
scar tissue grows excessively and invasively beyond the original wound borders. This …

Significance: Fibroblasts play a critical role in normal wound healing. Various extracellular
matrix (ECM) components, including collagens, fibrin, fibronectin, proteoglycans …

Hypertrophic scars and keloids can have significant detrimental effects on patients both
psychosocially and functionally. A careful identification of patient risk factors and a …

Wound healing involves a series of carefully modulated steps, from initial injury and blood
clot to the final reconstituted tissue or scar. A dynamic reciprocity exists throughout between …

Hypertrophic scars and keloids are firm, raised, erythematous plaques or nodules that
manifest when the cicatrix fails to properly heal. They result from pathologic wound healing …

With the burgeoning interest in hyaluronic acid (HA) in recent years, hyaluronidases
(HYALs) have come to light for their role in regulating catabolism of HA and its molecular …

Background The pathogenesis underlying keloid formation is still poorly understood.
Research has focused mostly on dermal abnormalities, while the epidermis has not yet been …

In recent years, hyaluronan (HA) has become an increasingly attractive substance as a non‐
immunogenic filler and scaffolding material in cosmetic dermatology. Despite its wide use for …

An essential element of tissue homeostasis is the response to injuries, cutaneous wound
healing being the most studied example. In the adults, wound healing aims at quickly …

All species have evolved mechanisms of repair to restore tissue function following injury.
Skin scarring is an inevitable and permanent endpoint for many postnatal organisms except …