Oxazole compounds containing nitrogen and oxygen atoms in the five-membered aromatic
ring are readily able to bind with a variety of enzymes and receptors in biological systems …

As one of the most representative hypoxic enzymes, nitroreductases (NTRs) play
momentous roles in malignant tumor progression, metastasis, invasion and angiogenesis …

Large tumours contain regions with very low intracellular O2 concentrations. Known as
hypoxia, this feature of tumours yields a highly reducing environment owing to the presence …

The mild and efficient palladium-catalyzed ortho C (sp2)–H diversification of (NH)-free 2-
substituted benzimidazole, quinazoline, and imidazopyridine is reported using hypervalent …

Listeria monocytogenes (Listeria) is a facultative pathogenic bacterium, and a sensitive
method for specific detection of Listeria is considered of clinically significant. However …

A copper‐catalyzed chelation‐assisted ortho‐nitration reaction of aryl derivtives has been
achieved, using benzazoles as efficient directing groups. The reaction is general and …

In clinical microbiology the speed with which pathogenic microorganisms may be detected
has a direct impact on patient health. One important strategy used in the laboratory is the …

A series of fluorogenic heterocyclic azides were prepared and assessed as reductase
substrates across a selection of Gram-negative and Gram-positive microorganisms. The …

Development of a rapid approach for universal microbial detection is required in the
healthcare, food and environmental sectors to aid with medical intervention, food safety and …

Аннотация Обоснование. Проблема синтеза новых эффективных биологически
активных соединений остается актуальной задачей современной химической науки …