Chemotherapy resistance in advanced ovarian cancer patients

R Pokhriyal, R Hariprasad, L Kumar… - Biomarkers in …, 2019 - journals.sagepub.com
Ovarian cancer is the seventh most common gynaecologic malignancy seen in women.
Majority of the patients with ovarian cancer are diagnosed at the advanced stage making …

Diagnosis and treatment of ovarian cancer

B Orr, RP Edwards - Hematology/Oncology Clinics, 2018 - hemonc.theclinics.com
The diagnosis and treatment planning for newly diagnosed ovarian adenocarcinomas are
unique among solid cancers. Ovarian cancer is insidious in presentation with few sentinel …

Ovarian cancer, version 2.2020, NCCN clinical practice guidelines in oncology

DK Armstrong, RD Alvarez, JN Bakkum-Gamez… - Journal of the National …, 2021 - jnccn.org
Epithelial ovarian cancer is the leading cause of death from gynecologic cancer in the
United States and is the country's fifth most common cause of cancer mortality in women. A …

Ovarian cancer, version 1.2016, NCCN clinical practice guidelines in oncology

RJ Morgan, DK Armstrong, RD Alvarez… - Journal of the National …, 2016 - jnccn.org
This selection from the NCCN Guidelines for Ovarian Cancer focuses on the less common
ovarian histopathologies (LCOHs), because new algorithms were added for LCOHs and …

Paclitaxel and its evolving role in the management of ovarian cancer

NC Kampan, MT Madondo, OM McNally… - BioMed research …, 2015 - Wiley Online Library
Paclitaxel, a class of taxane with microtubule stabilising ability, has remained with platinum
based therapy, the standard care for primary ovarian cancer management. A deeper …

Recent progress in the diagnosis and treatment of ovarian cancer

D Jelovac, DK Armstrong - CA: a cancer journal for clinicians, 2011 - Wiley Online Library
Epithelial ovarian cancer is the most lethal of the gynecologic malignancies, largely due to
the advanced stage at diagnosis in most patients. Screening strategies using ultrasound and …

Latest research and treatment of advanced-stage epithelial ovarian cancer

RL Coleman, BJ Monk, AK Sood… - Nature reviews Clinical …, 2013 - nature.com
The natural history of ovarian cancer continues to be characterized by late-stage
presentation, metastatic bulky disease burden and stagnant mortality statistics, despite …

Cyclophosphamide and cancer: golden anniversary

A Emadi, RJ Jones, RA Brodsky - Nature reviews Clinical oncology, 2009 - nature.com
Cyclophosphamide remains one of the most successful and widely utilized antineoplastic
drugs. Moreover, it is also a potent immunosuppressive agent and the most commonly used …

Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes

YK Wang, A Bashashati, MS Anglesio, DR Cochrane… - Nature …, 2017 - nature.com
We studied the whole-genome point mutation and structural variation patterns of 133 tumors
(59 high-grade serous (HGSC), 35 clear cell (CCOC), 29 endometrioid (ENOC), and 10 …

Survival impact of complete cytoreduction to no gross residual disease for advanced-stage ovarian cancer: a meta-analysis

SJ Chang, M Hodeib, J Chang, RE Bristow - Gynecologic oncology, 2013 - Elsevier
Objective To quantify the impact of complete cytoreduction to no gross residual disease on
overall survival among patients with advanced-stage ovarian cancer treated during the …