Use of carvedilol in hypertension: an update

G Leonetti, CG Egan - Vascular Health and Risk Management, 2012 - Taylor & Francis
β-blockers are effective antihypertensive agents and, together with diuretics, have been the
cornerstone of pioneering studies showing their benefits on cardiovascular morbidity and …

Labrasol-enriched nanoliposomal formulation: novel approach to improve oral absorption of water-insoluble drug, carvedilol

S Ghassemi, A Haeri, S Shahhosseini… - AAPS …, 2018 - Springer
The purpose of the current study was to develop a novel liposomal formulation to improve
the oral bioavailability of carvedilol, a Biopharmaceutics Classification System class II with …

A HPLC-MS/MS method for the determination of Nadolol in rat plasma: Development, validation, and application to pharmacokinetic study

N Kanjarla, B Pasupuleti, N Boggula… - … Journal of Mass …, 2023 - journals.sagepub.com
A sensitive validated method has been developed for the quantification of Nadolol in rat
plasma by high performance liquid chromatography coupled with tandem mass …

Chemically modified carbon paste sensor for the potentiometric determination of carvedilol in pharmaceutical and biological media

A Soleymanpour, M Ghasemian - Measurement, 2015 - Elsevier
The construction and performance characteristics of a novel potentiometric carbon paste
electrode based on incorporation of the ion-association complex of the carvedilol …

Utilization of adsorption technique in the development of oral delivery system of lipid based nanoparticles

S Chakraborty, D Shukla, PR Vuddanda… - Colloids and surfaces B …, 2010 - Elsevier
The objective of the present study was to employ suitable adsorbent with free flowing
characteristics for improving the stability and physical properties of solid lipid nanoparticles …

Floating microspheres of carvedilol as gastro retentive drug delivery system: 32 full factorial design and in vitro evaluation

MV Nila, MR Sudhir, TA Cinu, NA Aleykutty, S Jose - Drug delivery, 2014 - Taylor & Francis
Context: Designing a sustained release system for Carvedilol to increase its residence time
in the stomach. Objective: Preparation of floating microsphere by the emulsion solvent …

Association of common polymorphisms in β1-adrenergic receptor with antihypertensive response to carvedilol

D Si, J Wang, Y Xu, X Chen, M Zhang… - Journal of …, 2014 - journals.lww.com
Objectives: Marked interpatient variability exists in the blood pressure response to
carvedilol, a nonselective β-blocker. Here we evaluated the influence of 4 common …

C–N bond formation via Cu-catalyzed cross-coupling with boronic acids leading to methyl carbazole-3-carboxylate: synthesis of carbazole alkaloids

S Rasheed, DN Rao, KR Reddy, S Aravinda… - RSC …, 2014 - pubs.rsc.org
Copper promoted N-arylation of methyl 4-amino-3-iodobenzoate with boronic acids followed
by Pd-catalyzed intramolecular C–H arylation provides an efficient route to methyl carbazole …

Preparation and physicochemical characterization of binary and ternary ground mixtures of carvedilol with PVP and SLS aimed to improve the drug dissolution

N Bolourchian, Z Talamkhani… - Pharmaceutical …, 2019 - Taylor & Francis
The objective of the present study was to enhance the dissolution rate of carvedilol (CA), a
poorly water-soluble antihypertensive drug, using a co-grinding method in the presence of …

Tempol prevents cardiac oxidative damage and left ventricular dysfunction in the PPAR-α KO mouse

A Guellich, T Damy, M Conti, V Claes… - American Journal …, 2013 - journals.physiology.org
Peroxisome proliferator-activated receptor (PPAR)-α deletion induces a profound decrease
in MnSOD activity, leading to oxidative stress and left ventricular (LV) dysfunction. We tested …