Common themes and future challenges in understanding gene regulatory network evolution

I Schember, MS Halfon - Cells, 2022 - mdpi.com
A major driving force behind the evolution of species-specific traits and novel structures is
alterations in gene regulatory networks (GRNs). Comprehending evolution therefore …

Cortex cis-regulatory switches establish scale colour identity and pattern diversity in Heliconius

L Livraghi, JJ Hanly, SM Van Bellghem… - Elife, 2021 - elifesciences.org
In Heliconius butterflies, wing colour pattern diversity and scale types are controlled by a few
genes of large effect that regulate colour pattern switches between morphs and species …

[HTML][HTML] The loci of insect phenotypic evolution

V Courtier-Orgogozo - Current Opinion in Insect Science, 2023 - Elsevier
Highlights●Gephebase compiles more than 600 genes and mutations contributing to insect
natural variation●Our genetic knowledge is biased towards certain traits and insect …

A butterfly pan-genome reveals that a large amount of structural variation underlies the evolution of chromatin accessibility

AA Ruggieri, L Livraghi, JJ Lewis, E Evans… - Genome …, 2022 - genome.cshlp.org
Despite insertions and deletions being the most common structural variants (SVs) found
across genomes, not much is known about how much these SVs vary within populations and …

Evolution of stickleback spines through independent cis-regulatory changes at HOXDB

JI Wucherpfennig, TR Howes, JN Au, EH Au… - Nature Ecology & …, 2022 - nature.com
Understanding the mechanisms leading to new traits or additional features in organisms is a
fundamental goal of evolutionary biology. We show that HOXDB regulatory changes have …

Recurrent Loss of abaA, a Master Regulator of Asexual Development in Filamentous Fungi, Correlates with Changes in Genomic and Morphological Traits

ME Mead, AT Borowsky, B Joehnk… - Genome Biology and …, 2020 - academic.oup.com
Gene regulatory networks (GRNs) drive developmental and cellular differentiation, and
variation in their architectures gives rise to morphological diversity. Pioneering studies in …

Changes in locus wide repression underlie the evolution of Drosophila abdominal pigmentation

ID Méndez-González, TM Williams, M Rebeiz - PLoS genetics, 2023 - journals.plos.org
Changes in gene regulation represent an important path to generate developmental
differences affecting anatomical traits. Interspecific divergence in gene expression often …

Evolutionary expansion of apical extracellular matrix is required for the elongation of cells in a novel structure

SJ Smith, LA Davidson, M Rebeiz - Elife, 2020 - elifesciences.org
One of the fundamental gaps in our knowledge of how novel anatomical structures evolve is
understanding the origins of the morphogenetic processes that form these features. Here …

Drosophilids with darker cuticle have higher body temperature under light

L Freoa, LM Chevin, P Christol, S Méléard, M Rera… - Scientific Reports, 2023 - nature.com
Cuticle pigmentation was shown to be associated with body temperature for several
relatively large species of insects, but it was questioned for small insects. Here we used a …

Evolutionary dynamics of gene regulation

DH Erwin - Current topics in developmental biology, 2020 - Elsevier
The long controversy over the importance of changes in the regulatory genome has been
resolved with the recognition that such changes are a fundamental component of …