The end of AIDS: HIV infection as a chronic disease

SG Deeks, SR Lewin, DV Havlir - The lancet, 2013 - thelancet.com
The success of antiretroviral therapy has led some people to now ask whether the end of
AIDS is possible. For patients who are motivated to take therapy and who have access to …

Is HIV a model of accelerated or accentuated aging?

S Pathai, H Bajillan, AL Landay… - Journals of Gerontology …, 2014 - academic.oup.com
Background. Antiretroviral therapy has reduced the incidence of adverse events and early
mortality in HIV-infected persons. Despite these benefits, important comorbidities that …

Global and regional trends of people living with HIV aged 50 and over: Estimates and projections for 2000–2020

CS Autenrieth, EJ Beck, D Stelzle, C Mallouris… - PloS one, 2018 - journals.plos.org
Background The increasing numbers of people living with HIV (PLHIV) who are receiving
antiretroviral therapy (ART) have near normal life-expectancy, resulting in more people …

HIV treatment as prevention: systematic comparison of mathematical models of the potential impact of antiretroviral therapy on HIV incidence in South Africa

JW Eaton, LF Johnson, JA Salomon… - PLoS …, 2012 - journals.plos.org
Background Many mathematical models have investigated the impact of expanding access
to antiretroviral therapy (ART) on new HIV infections. Comparing results and conclusions …

The impact of antiretroviral treatment on the age composition of the HIV epidemic in sub-Saharan Africa

JAC Hontelez, SJ de Vlas, R Baltussen, ML Newell… - Aids, 2012 - journals.lww.com
Methods: We used STDSIM, a stochastic microsimulation model, and developed an
approach to represent HIV prevalence and treatment coverage in 43 countries in SSA, using …

Elimination of HIV in South Africa through expanded access to antiretroviral therapy: a model comparison study

JAC Hontelez, MN Lurie, T Bärnighausen… - PLoS …, 2013 - journals.plos.org
Background Expanded access to antiretroviral therapy (ART) using universal test and treat
(UTT) has been suggested as a strategy to eliminate HIV in South Africa within 7 y based on …

[PDF][PDF] HIV and aging--preparing for the challenges ahead

MD Till Bärnighausen, JN MIA - The New England journal of medicine, 2012 - natap.org
By 2015, half the US population living with human immunodeficiency virus (HIV) infection
will be older than 50 years of age. As antiretroviral therapy (ART) coverage continues to …

Prevalence of HIV and chronic comorbidities among older adults

J Negin, A Martiniuk, RG Cumming, N Naidoo… - Aids, 2012 - journals.lww.com
Objectives: Limited evidence is available on HIV, aging and comorbidities in sub-Saharan
Africa. This article describes the prevalence of HIV and chronic comorbidities among those …

Risk of coronary heart disease in patients with HIV infection

MV Zanni, J Schouten, SK Grinspoon… - Nature reviews …, 2014 - nature.com
The lives of individuals infected with HIV who have access to combination antiretroviral
therapy (cART) are substantially prolonged, which increases the risk of developing non …

Aging with HIV in Africa: the challenges of living longer

J Negin, T Bärnighausen, JD Lundgren, EJ Mills - Aids, 2012 - journals.lww.com
The global response to the HIV epidemic represents one of the greatest public health
achievements of this century. The successful scale-up of antiretroviral therapy (ART) …