Genome-wide panels of SNPs have recently been used in domestic animal species to map
and identify genes for many traits and to select genetically desirable livestock. This has led …

Genotype-to-phenotype mapping commonly focuses on two major classes of mutations:
single nucleotide polymorphisms (SNPs) and copy number variation (CNV). Here, we …

Domestic dog breeds are characterized by an unrivaled diversity of morphologic traits and
breed-associated behaviors resulting from human selective pressures. To identify the …

Next-generation sequencing technology provides novel opportunities for gathering genome-
scale sequence data in natural populations, laying the empirical foundation for the evolving …

The dog was the first domesticated animal but it remains uncertain when the domestication
process began and whether it occurred just once or multiple times across the Northern …

Dogs were present in the Americas before the arrival of European colonists, but the origin
and fate of these precontact dogs are largely unknown. We sequenced 71 mitochondrial and …

The domestic dog serves as an excellent model to investigate the genetic basis of disease.
More than 400 heritable traits analogous to human diseases have been described in dogs …

Domestic dogs exhibit tremendous phenotypic diversity, including a greater variation in body
size than any other terrestrial mammal. Here, we generate a high density map of canine …

Coat color and type are essential characteristics of domestic dog breeds. Although the
genetic basis of coat color has been well characterized, relatively little is known about the …

Retrotransposition of processed mRNAs is a common source of novel sequence acquired
during the evolution of genomes. Although the vast majority of retroposed gene copies, or …