Synthesis of Novel Hydrazide–Hydrazone Compounds and In Vitro and In Silico Investigation of Their Biological Activities against AChE, BChE, and hCA I and II
The abnormal levels of the human carbonic anhydrase isoenzymes I and II (hCA I and II)
and cholinesterase enzymes, namely, acetylcholinesterase (AChE) and …
and cholinesterase enzymes, namely, acetylcholinesterase (AChE) and …
Design, synthesis, characterization, molecular docking studies, molecular properties, toxicity, and bioactivity score prediction evaluation of novel chalcone-sulfonate …
A Korkmaz - Journal of Molecular Structure, 2023 - Elsevier
Novel chalcone-sulfonate hybrid derivatives were synthesized by a triethylamine-based
method and characterized 13 C NMR, 1 H NMR, and HRMS. The potential inhibitory effects …
method and characterized 13 C NMR, 1 H NMR, and HRMS. The potential inhibitory effects …
Novel Mannich bases derived from 1, 2, 4-triazoles: Design, synthesis, characterization, and glutathione S-transferase inhibition properties investigations
The reaction of variously substituted 1, 2, 4-triazole derivatives with morpholine and
formaldehyde represents an efficient and easy-to-set synthetic entry toward heterocyclic N …
formaldehyde represents an efficient and easy-to-set synthetic entry toward heterocyclic N …
Design, spectroscopic characterization, in silico and in vitro cytotoxic activity assessment of newly synthesized thymol Schiff base derivatives
Cancer is a global public health problem affecting millions of people every year. New
anticancer drug candidates are needed to overcome the resistance to drugs used in the …
anticancer drug candidates are needed to overcome the resistance to drugs used in the …
Synthesis, antioxidant, and anticholinesterase activities of novel N‐arylsulfonyl hydrazones bearing sulfonate ester scaffold
E Başaran - Journal of the Chinese Chemical Society, 2023 - Wiley Online Library
In this research, two new series of N‐arylsulfonyl hydrazone compounds (14–25)
possessing a sulfonate moiety were synthesized and characterized by elemental analysis …
possessing a sulfonate moiety were synthesized and characterized by elemental analysis …
Investigation of Newly Synthesized Fluorinated Isatin-Hydrazones by In Vitro Antiproliferative Activity, Molecular Docking, ADME Analysis, and e-Pharmacophore …
In this study, we investigated the in vitro antiproliferative activities and performed
computational studies of newly synthesized fluorinated isatin-hydrazones. The chemical …
computational studies of newly synthesized fluorinated isatin-hydrazones. The chemical …
[PDF][PDF] Syntheses of some hydrazones derived from 2-(aryloyloxy) benzaldehydes and 2, 4-dinitrophenylhydrazine and evaluation of their anticholinesterase and …
In this research, five novel hydrazone derivatives (2a-e) were obtained for the first time,
characterized and investigated for their antioxidant properties, and acetylcholinesterase …
characterized and investigated for their antioxidant properties, and acetylcholinesterase …
SOME NOVEL SCHIFF BASE DERIVATIVES AS PROMISING CHOLINESTERASE INHIBITORS WITH ANTIOXIDANT ACTIVITY AGAINST ALZHEIMER'S DISEASE …
In this manuscript, five novel Schiff base derivatives containing a pyrazolone ring and a
sulfonate moiety (6-10) except for 9 were designed, obtained for the first time and …
sulfonate moiety (6-10) except for 9 were designed, obtained for the first time and …