[HTML][HTML] CircRNAs: Pivotal modulators of TGF-β signalling in cancer pathogenesis

AA Bhat, G Gupta, R Dahiya, R Thapa, A Gahtori… - Non-coding RNA …, 2024 - Elsevier
The intricate molecular landscape of cancer pathogenesis continues to captivate
researchers worldwide, with Circular RNAs (circRNAs) emerging as pivotal players in the …

[HTML][HTML] CircIL4R activates the PI3K/AKT signaling pathway via the miR-761/TRIM29/PHLPP1 axis and promotes proliferation and metastasis in colorectal cancer

T Jiang, H Wang, L Liu, H Song, Y Zhang, J Wang… - Molecular Cancer, 2021 - Springer
Background Accumulating studies have revealed that aberrant expression of circular RNAs
(circRNAs) is widely involved in the tumorigenesis and progression of malignant cancers …

Quercetin modulates signal transductions and targets non-coding RNAs against cancer development

M Homayoonfal, H Gilasi, Z Asemi, MK Mahabady… - Cellular …, 2023 - Elsevier
In recent decades, various investigations have indicated that natural compounds have great
potential in the prevention and treatment of different chronic disorders including different …

[HTML][HTML] Nanoparticle-based RNAi therapeutics targeting cancer stem cells: Update and prospective

Y Tang, Y Chen, Z Zhang, B Tang, Z Zhou, H Chen - Pharmaceutics, 2021 - mdpi.com
Cancer stem cells (CSCs) are characterized by intrinsic self-renewal and tumorigenic
properties, and play important roles in tumor initiation, progression, and resistance to …

[HTML][HTML] Current molecular biology and therapeutic strategy status and prospects for circRNAs in HBV-associated hepatocellular carcinoma

R Liao, L Liu, J Zhou, X Wei, P Huang - Frontiers in Oncology, 2021 - frontiersin.org
Circular RNAs (circRNAs) are newly classified noncoding RNA (ncRNA) members with a
covalently closed continuous loop structure that are involved in immune responses against …

Role of DNA Methyltransferases (DNMTs) in metastasis

MZ Qureshi, UY Sabitaliyevich… - Cellular and …, 2022 - mail.cellmolbiol.org
The DNA methyltransferase (DNMT) family constitutes a conserved set of DNA-modifying
enzymes which have essential functions in the modulation of epigenetics. The fundamental …

Expression of FOXA1 gene regulates the proliferation and invasion of human gastric cancer cells

Y Dai, G Yang, L Yang, L Jiang, G Zheng… - Cellular and …, 2021 - mail.cellmolbiol.org
Forkhead box (FOX) transcription factors regulate the development of several human
cancers. However, the role and therapeutic potential of FOXA1 in gastric cancer is still …

[HTML][HTML] Understanding the roles of the hedgehog signaling pathway during T-cell lymphopoiesis and in T-cell acute lymphoblastic leukemia (T-ALL)

AM Martelli, F Paganelli, S Truocchio… - International journal of …, 2023 - mdpi.com
The Hedgehog (HH) signaling network is one of the main regulators of invertebrate and
vertebrate embryonic development. Along with other networks, such as NOTCH and WNT …

Regulatory role of circular RNAs in oral squamous cell carcinoma: Role of circular RNAs in the progression of OSCC

R Attar, K Noel, MA Romero… - Cellular and Molecular …, 2023 - cellmolbiol.org
OSCC is a genomically complicated disease and advancements in the modern era of
molecular oncology have enabled researchers to portray near-to-complete resolution of …

MicroRNAs and immunity

AR Naqvi, M Sarwat - Seminars in Cell & Developmental Biology, 2022 - Elsevier
Discovery of noncoding RNAs has refined our understanding of molecular mechanisms that
operate cellular processes and have advanced the field of molecular biology beyond protein …