[HTML][HTML] Sodium and its manifold impact on our immune system

K Jobin, DN Müller, J Jantsch, C Kurts - Trends in immunology, 2021 - cell.com
The Western diet is rich in salt, and a high salt diet (HSD) is suspected to be a risk factor for
cardiovascular diseases. It is now widely accepted that an experimental HSD can stimulate …

Urinary tract infection antibiotic resistance in the United States

TA Waller, SAL Pantin, AL Yenior… - Primary Care: Clinics …, 2018 - primarycare.theclinics.com
Urinary tract infection (UTI) is one of the most common conditions in both outpatient and
inpatient settings worldwide, where it has been noted to affect 150 million people annually. 1 …

[HTML][HTML] Recurrent urinary tract infections: unraveling the complicated environment of uncomplicated rUTIs

J Josephs-Spaulding, TJ Krogh, HC Rettig… - Frontiers in cellular …, 2021 - frontiersin.org
Urinary tract infections (UTIs) are frequent in humans, affecting the upper and lower urinary
tract. Present diagnosis relies on the positive culture of uropathogenic bacteria from urine …

A high-salt diet compromises antibacterial neutrophil responses through hormonal perturbation

K Jobin, NE Stumpf, S Schwab, M Eichler… - Science translational …, 2020 - science.org
The Western diet is rich in salt, which poses various health risks. A high-salt diet (HSD) can
stimulate immunity through the nuclear factor of activated T cells 5 (Nfat5)–signaling …

[HTML][HTML] Interleukin-6/Stat3 signaling has an essential role in the host antimicrobial response to urinary tract infection

CB Ching, S Gupta, B Li, H Cortado, N Mayne… - Kidney international, 2018 - Elsevier
The signaling networks regulating antimicrobial activity during urinary tract infection (UTI)
are incompletely understood. Interleukin-6 (IL-6) levels increase with UTI severity, but the …

Epigenetic mechanisms regulate innate immunity against uropathogenic and commensal-like Escherichia coli in the surrogate insect model Galleria mellonella

M Heitmueller, A Billion, U Dobrindt… - Infection and …, 2017 - Am Soc Microbiol
Innate-immunity-related genes in humans are activated during urinary tract infections (UTIs)
caused by pathogenic strains of Escherichia coli but are suppressed by commensals …

Biomarkers that differentiate false positive urinalyses from true urinary tract infection

N Shaikh, JM Martin, A Hoberman, M Skae… - Pediatric …, 2020 - Springer
Background The specificity of the leukocyte esterase test (87%) is suboptimal. The objective
of this study was to identify more specific screening tests that could reduce the number of …

Genetic diversity and biofilm formation analysis of Staphylococcus aureus causing urinary tract infections in Tehran, Iran

M Goudarzi, A Mohammadi, A Amirpour, M Fazeli… - The Journal of Infection …, 2019 - jidc.org
Introduction: Over the past decades, prevalence of biofilm-forming Staphylococcus aureus
strains has significantly increased in urinary tract infections. The aim of this study was to …

MANNosylation of Mesoporous Silica Nanoparticles Modifies TLR4 Localization and NF‐κB Translocation in T24 Bladder Cancer Cells

M Hohagen, L Sánchez, AJ Herbst… - Advanced …, 2024 - Wiley Online Library
D‐mannose is widely used as non‐antibiotic treatment for bacterial urinary tract infections.
This application is based on a well‐studied mechanism of binding to the type 1 bacterial pili …

New insights for febrile urinary tract infection (acute pyelonephritis) in children

KY Lee - Childhood Kidney Diseases, 2016 - koreascience.kr
Although asymptomatic bacteriuria, cystitis, and acute pyelonephritis (APN) have been
categorized as urinary tract infections (UTIs), the immunopathogenesis of each disease is …