The central nucleus of the amygdala and the construction of defensive modes across the threat-imminence continuum

JM Moscarello, MA Penzo - Nature Neuroscience, 2022 - nature.com
In nature, animals display defensive behaviors that reflect the spatiotemporal distance of
threats. Laboratory-based paradigms that elicit specific defensive responses in rodents have …

Behavioral and neurobiological mechanisms of pavlovian and instrumental extinction learning

ME Bouton, S Maren, GP McNally - Physiological reviews, 2021 - journals.physiology.org
This article reviews the behavioral neuroscience of extinction, the phenomenon in which a
behavior that has been acquired through Pavlovian or instrumental (operant) learning …

Context processing and the neurobiology of post-traumatic stress disorder

I Liberzon, JL Abelson - Neuron, 2016 - cell.com
Progress in clinical and affective neuroscience is redefining psychiatric illness as
symptomatic expression of cellular/molecular dysfunctions in specific brain circuits. Post …

[图书][B] Nonlinear pedagogy in skill acquisition: An introduction

JY Chow, K Davids, C Button, I Renshaw - 2021 - taylorfrancis.com
Nonlinear Pedagogy is a powerful paradigm for understanding human movement and for
designing effective teaching, coaching and training programmes in sport, exercise and …

The persistence and transience of memory

BA Richards, PW Frankland - Neuron, 2017 - cell.com
The predominant focus in the neurobiological study of memory has been on remembering
(persistence). However, recent studies have considered the neurobiology of forgetting …

Amygdala microcircuits controlling learned fear

S Duvarci, D Pare - Neuron, 2014 - cell.com
We review recent work on the role of intrinsic amygdala networks in the regulation of
classically conditioned defensive behaviors, commonly known as conditioned fear. These …

The birth, death and resurrection of avoidance: a reconceptualization of a troubled paradigm

JE LeDoux, J Moscarello, R Sears, V Campese - Molecular psychiatry, 2017 - nature.com
Research on avoidance conditioning began in the late 1930s as a way to use laboratory
experiments to better understand uncontrollable fear and anxiety. Avoidance was initially …

As soon as there was life, there was danger: the deep history of survival behaviours and the shallower history of consciousness

JE LeDoux - … Transactions of the Royal Society B, 2022 - royalsocietypublishing.org
It is often said that fear is a universal innate emotion that we humans have inherited from our
mammalian ancestors by virtue of having inherited conserved features of their nervous …

From Pavlov to PTSD: the extinction of conditioned fear in rodents, humans, and anxiety disorders

MB VanElzakker, MK Dahlgren, FC Davis… - Neurobiology of learning …, 2014 - Elsevier
Abstract Nearly 100 years ago, Ivan Pavlov demonstrated that dogs could learn to use a
neutral cue to predict a biologically relevant event: after repeated predictive pairings …

Stress and fear extinction

S Maren, A Holmes - Neuropsychopharmacology, 2016 - nature.com
Stress has a critical role in the development and expression of many psychiatric disorders,
and is a defining feature of posttraumatic stress disorder (PTSD). Stress also limits the …