Electrochemical immunosensors developed for amyloid-beta and tau proteins, leading biomarkers of Alzheimer's disease

A Sharma, L Angnes, N Sattarahmady, M Negahdary… - Biosensors, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common neurological disease and a serious cause of
dementia, which constitutes a threat to human health. The clinical evidence has found that …

Recent advances in electrochemical biosensors for the detection of Aβ42, a biomarker for Alzheimer disease diagnosis

M Ding, S Ding, D Du, X Wang, X Hu, P Guan… - TrAC Trends in …, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a long latency in
the" prodromal" stage, for which there are currently no effective treatments. It is generally …

Antigen-Mimic Nanoparticles in Ultrasensitive on-Chip Integrated Anti-p53 Antibody Quantification

S Kang, D Yuan, R Barber, JJ Davis - ACS sensors, 2024 - ACS Publications
As a tumor-suppressing protein, p53 plays a crucial role in preventing cancer development.
Its utility as an early cancer detection tool is significant, potentially enabling clinicians to …

Effect of microchannel geometry and linker molecules on surface immobilization efficiency of proteins in microfluidic devices

S Chakraborty, S Jaitpal, S Acharya, D Paul - Journal of Biotechnology, 2023 - Elsevier
One of the key metrics in the design of biosensors is the presence of an effective capture
layer. Surface-immobilized proteins (especially as a part of antibody-antigen combinations) …

[HTML][HTML] Tailoring single-molecule conductance with structured graphene electrodes

JG Fallaque, S Rodríguez-González, C Díaz… - Applied Surface …, 2024 - Elsevier
Modulation of electric currents through single-molecule junctions is usually achieved by
synthesis of molecules with desired functionalities, in conjunction with suitable molecule …

Competitive electrochemical aptasensor for high sensitivity detection of liver cancer marker GP73 based on rGO-Fc-PANi nanocomposites

G Li, B Wang, S Li, X Li, R Yan, X Tan, J Liang… - Bioelectrochemistry, 2024 - Elsevier
Abstract Golgi protein 73 (GP73) is a novel tumor marker in the early diagnosis and
prognosis of hepatocellular carcinoma (HCC). Herein, a competitive electrochemical …

Understanding the bonding mechanisms of organic molecules deposited on graphene for biosensing applications

EJ Legge, MM Ali, HY Abbasi, BP Reed… - The Journal of …, 2021 - pubs.aip.org
Graphene is an ideal material for biosensors due to the large surface area for multiple
bonding sites, the high electrical conductivity allowing for high sensitivity, and the high …

Single-molecule studies of alpha-synuclein and abeta in Parkinson's disease derived biofluids

D Emin - 2022 - repository.cam.ac.uk
Alzheimer's and Parkinson's disease are the two biggest neurodegenerative disorders,
characterised by an irreversible loss of neurons. To date, there are still no authorised …

Graphene based electrochemical biosensors for the detection of blood biomarkers of Alzheimer's disease

J Sethi - 2022 - plymouth.researchcommons.org
Alzheimer's disease (AD) is a neurodegenerative disorder that affects millions of people
around the world with no available treatments to cure, reverse or even slow down the …

Detección electroquímica de α-Pirrolidinopentiofenona (α-PVP) Y 3, 4-Metilendioximetanfetamina (MDMA) mediante un biosensor electroquímico basado en la …

AF Lugo Vargas - repositorio.unal.edu.co
En el presente estudio se exploró mediante la técnica de voltamperometría diferencial de
pulsos (VDP) la respuesta electroquímica de α-pirrolidinopentiofenona (α-PVP) y 3, 4 …