Human CEACAM1 is targeted by a Streptococcus pyogenes adhesin implicated in puerperal sepsis pathogenesis
Life-threatening bacterial infections in women after childbirth, known as puerperal sepsis,
resulted in classical epidemics and remain a global health problem. While outbreaks of …
resulted in classical epidemics and remain a global health problem. While outbreaks of …
The intricate pathogenicity of group a Streptococcus: A comprehensive update
H Bergsten, V Nizet - Virulence, 2024 - Taylor & Francis
ABSTRACT Group A Streptococcus (GAS) is a versatile pathogen that targets human
lymphoid, decidual, skin, and soft tissues. Recent advancements have shed light on its …
lymphoid, decidual, skin, and soft tissues. Recent advancements have shed light on its …
Pangenome evaluation of gene essentiality in Streptococcus pyogenes
Bacterial species often consist of strains with variable gene content, collectively referred to
as the pangenome. Variations in the genetic makeup of strains can alter bacterial physiology …
as the pangenome. Variations in the genetic makeup of strains can alter bacterial physiology …
Associations of vaginal microbiota with the onset, severity, and type of symptoms of genitourinary syndrome of menopause in women
Q Zeng, H Shu, H Pan, Y Zhang, L Fan… - Frontiers in Cellular …, 2024 - frontiersin.org
Introduction Genitourinary syndrome of menopause (GSM) describes the symptoms and
signs resulting from the effect of estrogen deficiency on the female genitourinary tract …
signs resulting from the effect of estrogen deficiency on the female genitourinary tract …
Genome-Wide Transposon Mutagenesis Screens Identify Group A Streptococcus Genes Affecting Susceptibility to β-Lactam Antibiotics
L Zhu, JM Eraso, RE Mangham… - Journal of …, 2022 - Am Soc Microbiol
Group A streptococcus (GAS) is a Gram-positive human bacterial pathogen responsible for
more than 700 million infections annually worldwide. Beta-lactam antibiotics are the primary …
more than 700 million infections annually worldwide. Beta-lactam antibiotics are the primary …
The streptococcal phase-variable type I restriction modification system SsuCC20p dictates the methylome of Streptococcus suis impacting the transcriptome and …
Phase-variable type I restriction modification (RM) systems are epigenetic regulatory
systems that have been identified in numerous human bacterial pathogens. We previously …
systems that have been identified in numerous human bacterial pathogens. We previously …
HupZ, a unique heme-binding protein, enhances group A Streptococcus fitness during mucosal colonization
Group A Streptococcus (GAS) is a major pathogen that causes simple and invasive
infections. GAS requires iron for metabolic processes and pathogenesis, and heme is its …
infections. GAS requires iron for metabolic processes and pathogenesis, and heme is its …
A family cluster of Streptococcus pyogenes associated with a fatal early-onset neonatal sepsis
F Novazzi, L Colombini… - Clinical …, 2024 - clinicalmicrobiologyandinfection …
Streptococcus pyogenes (Group A Streptococcus [GAS]) is responsible for millions of
infections and more than 500 000 deaths worldwide annually [1]. Generally, the primary site …
infections and more than 500 000 deaths worldwide annually [1]. Generally, the primary site …
[HTML][HTML] Streptococcus pyogenes genes that promote pharyngitis in primates
Streptococcus pyogenes (group A streptococcus; GAS) causes 600 million cases of
pharyngitis annually worldwide. There is no licensed human GAS vaccine despite a century …
pharyngitis annually worldwide. There is no licensed human GAS vaccine despite a century …
Streptococcus pyogenes infects human endometrium by limiting the innate immune response
Group A Streptococcus (GAS), a Gram-positive human-specific pathogen, yields 517,000
deaths annually worldwide, including 163,000 due to invasive infections and among them …
deaths annually worldwide, including 163,000 due to invasive infections and among them …