Off-label use of medication may be presented in these guidelines if a sufficient level of
evidence shows that it can be considered medically appropriate to a given condition and if …

for digital applications (smartphones, etc.). These versions are abridged and thus, for more
detailed information, the user should always access to the full text version of the guidelines …

• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Antibiotics are used to fight pathogens but also target commensal bacteria, disturbing the
composition of gut microbiota and causing dysbiosis and disease. Despite this well-known …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through March 1, 2020. Searches …

Health professionals are encouraged to take the ESC/EACTS Guidelines fully into account
when exercising their clinical judgment, as well as in the determination and the …

Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

The microbiology, epidemiology, diagnostics, and treatment of infective endocarditis (IE)
have changed significantly since the Duke Criteria were published in 1994 and modified in …

Abstract Aims The EURO-ENDO registry aimed to study the management and outcomes of
patients with infective endocarditis (IE). Methods and results Prospective cohort of 3116 …

Recenzenci dokumentu: Marco Roffi, koordynator recenzji ze strony CPG (Szwajcaria),
Ottavio Alfieri1, koordynator recenzji ze strony EACTS (Włochy), Stefan Agewall (Norwegia) …