Cerebral small vessel disease (SVD) is common during ageing and can present as stroke,
cognitive decline, neurobehavioural symptoms, or functional impairment. SVD frequently …

Cerebral microbleeds (CMBs) are defined as hypointense foci visible on T2*-weighted and
susceptible-weighted MRI sequences. CMBs are increasingly recognised with the …

Importance Covert vascular brain injury (VBI) is highly prevalent in community-dwelling
older persons, but its clinical and therapeutic implications are debated. Objective To better …

Background Cerebral microbleeds can confer a high risk of intracerebral hemorrhage,
ischemic stroke, death and dementia, but estimated risks remain imprecise and often …

Objective: Alzheimer's disease and vascular dementia are responsible for more than 80% of
dementia cases. These two conditions share common risk factors including hypertension …

Background and Purpose: The causes of recurrent ischemic stroke despite anticoagulation
for atrial fibrillation are uncertain but might include small vessel occlusion. We investigated …

Background Findings from the RESTART trial suggest that starting antiplatelet therapy might
reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding …

The past decade has seen significant advances in stroke prevention. These advances
include new antithrombotic agents, new options for dyslipidemia treatment, and novel …

Importance The reported associations of cerebral microbleeds with recurrent stroke and
intracerebral hemorrhage have raised concerns regarding antithrombotic treatment in …

Balancing the risks of recurrent ischemia and antithrombotic-associated bleeding,
particularly intracranial hemorrhage (ICH), is a key challenge in the secondary prevention of …