Polyethylene glycol (PEG) is a versatile polymer that is widely used as an additive in foods
and cosmetics, and as a carrier in PEGylated therapeutics. Even though PEG is thought to …

The oral route is the most common route for drug administration. It is the most preferred
route, due to its advantages, such as non-invasiveness, patient compliance and …

Introduction: Polyethylene glycol (PEG) is a polymer of choice in drug delivery systems. This
USFDA-approved polymer is popular due to its tunable properties and well-established …

The present report focuses on the various aspects of oral delivery of anticancer drugs. The
significance of oral delivery in cancer therapeutics has been highlighted which principally …

Nonionic surfactant based vesicles (niosomes) are novel drug delivery systems formed from
the self‐assembly of nonionic amphiphiles in aqueous media. In the present study niosomal …

The use of lipid nanocapsules (LNCs) has enabled an improvement of the oral
bioavailability of paclitaxel (Ptx). However, mechanisms that support this recent observation …

Introduction: Paclitaxel (PTX) is one of the most effective broad-spectrum chemotherapeutic
agents in the treatment of cancers. However, its clinical application has been limited due to …

One of the main difficulties in the management of patients with advanced
cholangiocarcinoma (CCA) is their poor response to available chemotherapy. This is the …

Inhibition of efflux pumps is an emerging approach in cancer therapy and drug delivery.
Since it has been discovered that polymeric pharmaceutical excipients such as Tweens® or …

Considerable research efforts have been directed towards understanding the enigma of P-
glycoprotein (P-gp) in drug development and delivery. P-gp is a multi-specific drug efflux …