Engineering microrobots for targeted cancer therapies from a medical perspective

CK Schmidt, M Medina-Sánchez… - Nature …, 2020 - nature.com
Systemic chemotherapy remains the backbone of many cancer treatments. Due to its
untargeted nature and the severe side effects it can cause, numerous nanomedicine …

Design and synthesis of SERS materials for in vivo molecular imaging and biosensing

Q Li, H Huo, Y Wu, L Chen, L Su, X Zhang… - Advanced …, 2023 - Wiley Online Library
Surface‐enhanced Raman scattering (SERS) is a feasible and ultra‐sensitive method for
biomedical imaging and disease diagnosis. SERS is widely applied to in vivo imaging due …

Enzyme-based mesoporous nanomotors with near-infrared optical brakes

M Liu, L Chen, Z Zhao, M Liu, T Zhao… - Journal of the …, 2022 - ACS Publications
As one of the most important parameters of the nanomotors' motion, precise speed control of
enzyme-based nanomotors is highly desirable in many bioapplications. However, owing to …

Multifunctional 3D‐printed pollen grain‐inspired hydrogel microrobots for on‐demand anchoring and cargo delivery

YW Lee, JK Kim, U Bozuyuk, NO Dogan… - Advanced …, 2023 - Wiley Online Library
While a majority of wireless microrobots have shown multi‐responsiveness to implement
complex biomedical functions, their functional executions are strongly dependent on the …

Urease-powered nanobots for radionuclide bladder cancer therapy

C Simó, M Serra-Casablancas, AC Hortelao… - Nature …, 2024 - nature.com
Bladder cancer treatment via intravesical drug administration achieves reasonable survival
rates but suffers from low therapeutic efficacy. To address the latter, self-propelled …

Defect-induced activity enhancement of enzyme-encapsulated metal-organic frameworks revealed in microfluidic gradient mixing synthesis

C Hu, Y Bai, M Hou, Y Wang, L Wang, X Cao… - Science …, 2020 - science.org
Mimicking the cellular environment, metal-organic frameworks (MOFs) are promising for
encapsulating enzymes for general applications in environments often unfavorable for …

Micro-and nanomotors as active environmental microcleaners and sensors

J Parmar, D Vilela, K Villa, J Wang… - Journal of the American …, 2018 - ACS Publications
The quest to provide clean water to the entire population has led to a tremendous boost in
the development of environmental nanotechnology. Toward this end, micro/nanomotors are …

Light-driven carbon nitride microswimmers with propulsion in biological and ionic media and responsive on-demand drug delivery

V Sridhar, F Podjaski, Y Alapan, J Kröger… - Science robotics, 2022 - science.org
We propose two-dimensional poly (heptazine imide)(PHI) carbon nitride microparticles as
light-driven microswimmers in various ionic and biological media. Their high-speed (15 to …

Autonomous Treatment of Bacterial Infections in Vivo Using Antimicrobial Micro- and Nanomotors

X Arqué, MDT Torres, T Patiño, A Boaro, S Sánchez… - ACS …, 2022 - ACS Publications
The increasing resistance of bacteria to existing antibiotics constitutes a major public health
threat globally. Most current antibiotic treatments are hindered by poor delivery to the …

Enzyme-powered liquid metal nanobots endowed with multiple biomedical functions

D Xu, J Hu, X Pan, S Sanchez, X Yan, X Ma - ACS nano, 2021 - ACS Publications
Catalytically powered micro/nanobots (MNBs) can perform active movement by harnessing
energy from in situ chemical reactions and show tremendous potential in biomedical …