Hydrophobic mismatch drives self-organization of designer proteins into synthetic membranes

JA Peruzzi, J Steinkühler, TQ Vu, TF Gunnels… - Nature …, 2024 - nature.com
The organization of membrane proteins between and within membrane-bound
compartments is critical to cellular function. Yet we lack approaches to regulate this …

HaloTag display enables quantitative single-particle characterization and functionalization of engineered extracellular vesicles

RE Mitrut, DM Stranford, BN DiBiase, JM Chan… - bioRxiv, 2023 - biorxiv.org
Extracellular vesicles (EVs) play key roles in diverse biological processes, transport
biomolecules between cells, and have been engineered for therapeutic applications. A …