Sepsis is defined as life-threatening organ dysfunction caused by a host response to
infection and represents a spectrum of disease severity ranging from bacteremia to septic …

Sepsis is a significant public health concern, particularly affecting individuals above 70
years in developed countries. This is a crucial fact due to the increasing aging population …

Objective To date, there are no studies regarding the lactylation profile and its role in
critically ill patients. Thus, we aimed to examine expression of histone H3 lysine 18 (H3K18) …

Background Elderly patients with sepsis have many comorbidities, and the clinical reaction
is not obvious. Thus, clinical treatment is difficult. We planned to use the laboratory test …

Background Due to the high incidence and mortality of sepsis-associated acute kidney
injury, a significant number of studies have explored the causes of sepsis-associated acute …

Sepsis is a common risk factor for acute kidney injury (AKI). Bone marrow-derived
mesenchymal stem cells (BMSCs) bear multi-directional differentiation potential. This study …

Methods We conducted a retrospective study at the ED of Siriraj Hospital Mahidol University
in Bangkok, Thailand. Patients over 18 years old who were diagnosed and treated for sepsis …

Sepsis has a complex pathophysiology in which both excessive and refractory inflammatory
responses are hallmark features. Pro-inflammatory cytokine responses during the early …

Significance: Both incidence and mortality rates of sepsis significantly increase with
advanced age, and the majority of sepsis patients are late middle-aged or older. With the …

Sepsis currently remains a major contributor to mortality in the intensive care unit (ICU), with
48.9 million cases reported globally and a mortality rate of 22.5% in 2017, accounting for …