Multicomponent reaction design in the quest for molecular complexity and diversity
E Ruijter, R Scheffelaar… - Angewandte Chemie …, 2011 - Wiley Online Library
Multicomponent reactions have become increasingly popular as tools for the rapid
generation of small‐molecule libraries. However, to ensure sufficient molecular diversity and …
generation of small‐molecule libraries. However, to ensure sufficient molecular diversity and …
Higher-order multicomponent reactions: beyond four reactants
S Brauch, SS van Berkel, B Westermann - Chemical Society Reviews, 2013 - pubs.rsc.org
Multicomponent reactions (MCRs) are by far the most successful class of reactions leading
to high structural diversity and molecular complexity through a single transformation. As part …
to high structural diversity and molecular complexity through a single transformation. As part …
Facile and One-Pot Access to Diverse and Densely Functionalized 2-Amino-3-cyano-4H-pyrans and Pyran-Annulated Heterocyclic Scaffolds via an Eco-Friendly …
G Brahmachari, B Banerjee - ACS Sustainable Chemistry & …, 2014 - ACS Publications
A simple, straightforward, and highly efficient multicomponent one-pot synthesis of a
pharmaceutically interesting diverse kind of functionalized 2-amino-3-cyano-4 H-pyrans and …
pharmaceutically interesting diverse kind of functionalized 2-amino-3-cyano-4 H-pyrans and …
Formaldehyde in multicomponent reactions
Acting as a C1 building block, formaldehyde is of great significance in organic synthesis. It is
also a key feedstock in several industries, such as resins, polymers, adhesives, and paints …
also a key feedstock in several industries, such as resins, polymers, adhesives, and paints …
Bismuth nitrate-catalyzed multicomponent reaction for efficient and one-pot synthesis of densely functionalized piperidine scaffolds at room temperature
G Brahmachari, S Das - Tetrahedron Letters, 2012 - Elsevier
A simple, straightforward, and highly efficient diastereoselective multicomponent one-pot
synthesis of a series of pharmaceutically interesting functionalized piperidine derivatives …
synthesis of a series of pharmaceutically interesting functionalized piperidine derivatives …
Mehrkomponentenreaktionen als Weg zu molekularer Komplexität und Diversität
E Ruijter, R Scheffelaar, RVA Orru - Angewandte Chemie, 2011 - Wiley Online Library
Mehrkomponentenreaktionen haben sich zu sehr populären Hilfsmitteln für die schnelle
Erzeugung von Bibliotheken niedermolekularer organischer Verbindungen entwickelt. Um …
Erzeugung von Bibliotheken niedermolekularer organischer Verbindungen entwickelt. Um …
Cerium ammonium nitrate-catalyzed multicomponent reaction for efficient synthesis of functionalized tetrahydropyridines
HJ Wang, LP Mo, ZH Zhang - ACS Combinatorial Science, 2011 - ACS Publications
A highly atom-economic one-pot synthesis of functionalized tetrahydropyridines by a
multicomponent condensation reaction of β-keto ester, two equivalents of aromatic …
multicomponent condensation reaction of β-keto ester, two equivalents of aromatic …
Recent advances in asymmetric isocyanide‐based multicomponent reactions
SS van Berkel, BGM Bögels… - European Journal of …, 2012 - Wiley Online Library
Isocyanide‐based multicomponent reactions (IMCRs) can be considered one of the
breakthrough reaction classes of the last century. Moreover, asymmetric IMCRs have …
breakthrough reaction classes of the last century. Moreover, asymmetric IMCRs have …
Cyclic imines in Ugi and Ugi-type reactions
Ugi four-component reactions (U-4CRs) are widely recognized as being highly efficient for
the synthesis of pseudopeptides. However, the products of these reactions are not so …
the synthesis of pseudopeptides. However, the products of these reactions are not so …
Facile and One-Pot Access of 3,3-Bis(indol-3-yl)indolin-2-ones and 2,2-Bis(indol-3-yl)acenaphthylen-1(2H)-one Derivatives via an Eco-Friendly Pseudo …
G Brahmachari, B Banerjee - ACS Sustainable Chemistry & …, 2014 - ACS Publications
A simple, straightforward, and highly efficient pseudo-three-component one-pot synthesis of
a series of pharmaceutically interesting functionalized 3, 3-bis (indol-3-yl) indolin-2-ones (3a …
a series of pharmaceutically interesting functionalized 3, 3-bis (indol-3-yl) indolin-2-ones (3a …