Microbial bioproduction of chemicals, proteins, and primary metabolites from cheap carbon
sources is currently an advancing area in industrial research. The model yeast …

Pichia pastoris (syn. Komagataella spp.) has attracted extensive attention as an efficient
platform for recombinant protein (RP) production. For obtaining a higher protein titer, many …

Abstract Background Pichia pastoris (syn. Komagataella phaffii) is a widely used generally
recognized as safe host for heterologous expression of proteins in both industry and …

Highlights•Genome editing technologies were adapted for gene disruption, deletion and
editing in P. pastoris.•New chassis strains for facilitated expression of complex …

Baicalein and oroxylin A are well-known medicinal 4′-deoxyflavones found mainly in the
roots of traditional medicinal plant Scutellaria baicalensis Georgi. However, extraction from …

Lycopene is widely used in cosmetics, food, and nutritional supplements. Microbial
production of lycopene has been intensively studied. However, few metabolic engineering …

Background The biological synthesis of high value compounds in industry through
metabolically engineered microorganism factories has received increasing attention in …

Pichia pastoris has been widely exploited for the heterologous expression of proteins in both
industry and academia. Recently, it has been shown to be a potentially good chassis host for …

Patchoulol, a plant-derived sesquiterpene compound, is widely used in perfumes,
cosmetics, and pharmaceuticals. Microbial production provides a promising alternative …

Lycopene is a highly valued carotenoid with wide applications in various industries. The
market demand for lycopene promotes research in metabolic engineering of heterologous …