[HTML][HTML] MicroRNA: A signature for cancer progression

BM Hussen, HJ Hidayat, A Salihi, DK Sabir… - Biomedicine & …, 2021 - Elsevier
MicroRNAs (miRNAs) are a group of small non-coding RNAs that post-transcriptionally
control expression of genes by targeting mRNAs. miRNA alterations partake in the …

MicroRNA let-7 and viral infections: focus on mechanisms of action

A Letafati, S Najafi, M Mottahedi, M Karimzadeh… - Cellular & Molecular …, 2022 - Springer
MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells

Y Wang, Y Li, JI Toth, MD Petroski, Z Zhang… - Nature cell …, 2014 - nature.com
Abstract N 6-methyladenosine (m6A) has been identified as the most abundant internal
modification of messenger RNA in eukaryotes. m6A modification is involved in cell fate …

The imprinted H19 lncRNA antagonizes let-7 microRNAs

AN Kallen, XB Zhou, J Xu, C Qiao, J Ma, L Yan, L Lu… - Molecular cell, 2013 - cell.com
Abundantly expressed in fetal tissues and adult muscle, the developmentally regulated H19
long noncoding RNA (lncRNA) has been implicated in human genetic disorders and cancer …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

The Lin28/let-7 axis regulates glucose metabolism

H Zhu, N Shyh-Chang, AV Segrè, G Shinoda, SP Shah… - Cell, 2011 - cell.com
The let-7 tumor suppressor microRNAs are known for their regulation of oncogenes, while
the RNA-binding proteins Lin28a/b promote malignancy by inhibiting let-7 biogenesis. We …

Let-7 as biomarker, prognostic indicator, and therapy for precision medicine in cancer

E Chirshev, KC Oberg, YJ Ioffe… - Clinical and translational …, 2019 - Springer
Abnormal regulation and expression of microRNAs (miRNAs) has been documented in
various diseases including cancer. The miRNA let-7 (MIRLET7) family controls …

MicroRNAs in cancer

R Garzon, GA Calin, CM Croce - Annual review of medicine, 2009 - annualreviews.org
MicroRNAs (miRNAs) are small, noncoding RNAs with important functions in development,
cell differentiation, and regulation of cell cycle and apoptosis. MiRNA expression is …

The let-7 family of microRNAs

S Roush, FJ Slack - Trends in cell biology, 2008 - cell.com
The first two known microRNAs (miRNAs), lin-4 and let-7, were originally discovered in the
nematode Caenorhabditis elegans and control the timing of stem-cell division and …

MicroRNAs and epigenetics

F Sato, S Tsuchiya, SJ Meltzer, K Shimizu - The FEBS journal, 2011 - Wiley Online Library
MicroRNAs (miRNAs) comprise species of short noncoding RNA that regulate gene
expression post‐transcriptionally. Recent studies have demonstrated that epigenetic …