Attention-deficit/hyperactivity disorder (ADHD) and Bipolar Disorder (BD) are common
mental disorders with a high degree of comorbidity. However, no systematic review with …

Objective Bipolar disorder (BD) is a chronic mental health disorder with significant morbidity
and mortality. Age at onset (AAO) may be a key variable in delineating more homogeneous …

Background Early-onset bipolar disorder (BD) is a complex psychiatric illness characterized
by mood swings, irritability and functional impairments. To improve our understanding of the …

Aims This article examines the ongoing debate concerning the diagnosis of bipolar disorder
in children and adolescents. This contentious issue has generated robust discussion over …

Individuals suffering from major mental health disorders, including schizophrenia spectrum
disorders, bipolar disorder, and borderline personality disorder, often experience difficulties …

Background Despite the well-documented negative impact of untreated bipolar illness,
approaches to early intervention in childhood-onset bipolar and related disorders are not …

Objectives: Paediatric bipolar disorder–bipolar disorder occurring in prepubertal children–is
a diagnosis subject to considerable controversy. Whilst historically considered to be very …

Background 'Pediatric bipolar disorder'(PBD) is a controversial diagnosis with varying rates
of clinical diagnosis. A highly cited meta-analysis (Van Meter et al. 2011) of a dozen …

Another problem with the diagnosis of PBD is that is hinges on 'irritability'as a defining
symptom. This poses difficulties because, in practice, irritability is a common feature of many …

Professor Malhi and colleagues (this issue) accept my overall critique of the construct of
paediatric bipolar disorder and endorse the substantive content of my article (Connors …