Background Many high-throughput experiments compare two phenotypes such as disease
vs. healthy, with the goal of understanding the underlying biological phenomena …

Pathway analysis has become the first choice for gaining insight into the underlying biology
of differentially expressed genes and proteins, as it reduces complexity and has increased …

Background Papillary renal-cell carcinoma, which accounts for 15 to 20% of renal-cell
carcinomas, is a heterogeneous disease that consists of various types of renal cancer …

Outcomes of high-throughput biological experiments are typically interpreted by statistical
testing for enriched gene functional categories defined by the Gene Ontology (GO). The …

Integrin receptor activation initiates the formation of integrin adhesion complexes (IACs) at
the cell membrane that transduce adhesion-dependent signals to control a multitude of …

DAVID bioinformatics resources consists of an integrated biological knowledgebase and
analytic tools aimed at systematically extracting biological meaning from large gene/protein …

Functional analysis of large gene lists, derived in most cases from emerging high-throughput
genomic, proteomic and bioinformatics scanning approaches, is still a challenging and …

Fibrosis is defined by the overgrowth, hardening, and/or scarring of various tissues and is
attributed to excess deposition of extracellular matrix components including collagen …

Abstract The DAVID Gene Functional Classification Tool http://david. abcc. ncifcrf. gov uses
a novel agglomeration algorithm to condense a list of genes or associated biological terms …

All tools in the DAVID Bioinformatics Resources aim to provide functional interpretation of
large lists of genes derived from genomic studies. The newly updated DAVID Bioinformatics …