Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging

K Jomova, R Raptova, SY Alomar, SH Alwasel… - Archives of …, 2023 - Springer
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Nrf2 and oxidative stress: A general overview of mechanisms and implications in human disease

V Ngo, ML Duennwald - Antioxidants, 2022 - mdpi.com
Organisms are continually exposed to exogenous and endogenous sources of reactive
oxygen species (ROS) and other oxidants that have both beneficial and deleterious effects …

A common feature of pesticides: oxidative stress—the role of oxidative stress in pesticide‐induced toxicity

RO Sule, L Condon, AV Gomes - Oxidative medicine and …, 2022 - Wiley Online Library
Pesticides are important chemicals or biological agents that deter or kill pests. The use of
pesticides has continued to increase as it is still considered the most effective method to …

Reactive oxygen species and antioxidant defense in plants under abiotic stress: Revisiting the crucial role of a universal defense regulator

M Hasanuzzaman, MHMB Bhuyan, F Zulfiqar, A Raza… - Antioxidants, 2020 - mdpi.com
Global climate change and associated adverse abiotic stress conditions, such as drought,
salinity, heavy metals, waterlogging, extreme temperatures, oxygen deprivation, etc., greatly …

Functions of ROS in macrophages and antimicrobial immunity

M Herb, M Schramm - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are a chemically defined group of reactive molecules
derived from molecular oxygen. ROS are involved in a plethora of processes in cells in all …

Mitochondrial oxidative stress—a causative factor and therapeutic target in many diseases

P Kowalczyk, D Sulejczak, P Kleczkowska… - International journal of …, 2021 - mdpi.com
The excessive formation of reactive oxygen species (ROS) and impairment of defensive
antioxidant systems leads to a condition known as oxidative stress. The main source of free …

ROS in cancer therapy: the bright side of the moon

B Perillo, M Di Donato, A Pezone, E Di Zazzo… - … & molecular medicine, 2020 - nature.com
Reactive oxygen species (ROS) constitute a group of highly reactive molecules that have
evolved as regulators of important signaling pathways. It is now well accepted that moderate …

Regulation of reactive oxygen species during salt stress in plants and their crosstalk with other signaling molecules—Current perspectives and future directions

MS Kesawat, N Satheesh, BS Kherawat, A Kumar… - Plants, 2023 - mdpi.com
Salt stress is a severe type of environmental stress. It adversely affects agricultural
production worldwide. The overproduction of reactive oxygen species (ROS) is the most …

Superoxide radicals in the execution of cell death

J Fujii, T Homma, T Osaki - Antioxidants, 2022 - mdpi.com
Superoxide is a primary oxygen radical that is produced when an oxygen molecule receives
one electron. Superoxide dismutase (SOD) plays a primary role in the cellular defense …

RONS and oxidative stress: An overview of basic concepts

AK Aranda-Rivera, A Cruz-Gregorio… - Oxygen, 2022 - mdpi.com
Oxidative stress (OS) has greatly interested the research community in understanding
damaging processes occurring in cells. OS is triggered by an imbalance between reactive …