Aotus monkeys: their great value for anti-malaria vaccines and drug testing

S Herrera, BL Perlaza, A Bonelo… - International journal for …, 2002 - Elsevier
Non-human primates represent a valuable resource for testing potential vaccines
candidates and drugs for human use. Malaria remains one of the greatest burdens for the …

A multilateral effort to develop DNA vaccines against falciparum malaria

S Kumar, JE Epstein, TL Richie, FK Nkrumah… - Trends in …, 2002 - cell.com
Scientists from several organizations worldwide are working together to develop a
multistage, multigene DNA-based vaccine against Plasmodium falciparum malaria. This …

Reduced immunogenicity of DNA vaccine plasmids in mixtures

M Sedegah, Y Charoenvit, L Minh, M Belmonte… - Gene therapy, 2004 - nature.com
We measured the ability of nine DNA vaccine plasmids encoding candidate malaria vaccine
antigens to induce antibodies and interferon-γ responses when delivered alone or in a …

The human malaria-Aotus monkey model: a historical perspective in antimalarial chemotherapy research at the Gorgas Memorial Laboratory-Panama

N Obaldía III - Antimicrobial Agents and Chemotherapy, 2024 - Am Soc Microbiol
The human malaria-Aotus monkey model has served the malaria research community since
its inception in 1966 at the Gorgas Memorial Laboratory (GML) in Panama. Spanning over …

Vaccination of mice with DNA vaccine induces the immune response and partial protection against T. spiralis infection

ZQ Wang, J Cui, HY Wei, HM Han, HW Zhang, YL Li - Vaccine, 2006 - Elsevier
Trichinellosis is a serious parasitic zoonosis which is widely distributed in the world. Pork
still is the predominant source of outbreaks of human trichinellosis in many countries …

Is genetic vaccination against allergy possible?

R Weiss, S Scheiblhofer, M Gabler, F Ferreira… - International archives of …, 2006 - karger.com
Genetic immunization has proven a powerful method to induce antiallergic immune
responses. The underlying functional principle has been described to be based on the …

DNA vaccines and their application against parasites-promise, limitations and potential solutions Peter M. Smooker', Adam Rainczuk², Nicholas Kennedy², and Terry …

PM Smooker, A Rainczuk, N Kennedy… - Biotechnology annual …, 2004 - books.google.com
DNA or nucleic acid vaccines are being evaluated for efficacy against a range of parasitic
diseases. Data from studies in rodent model systems have provided proof of principle that …

DNA vaccines: a rational design against parasitic diseases

JA Carvalho, J Rodgers, J Atouguia… - Expert Review of …, 2010 - Taylor & Francis
Parasitic diseases are one of the most devastating causes of morbidity and mortality
worldwide. Although immunization against these infections would be an ideal solution, the …

[HTML][HTML] Molecular and immunological tools for the evaluation of the cellular immune response in the neotropical monkey Saimiri sciureus, a non-human primate …

EKP Riccio, LR Pratt-Riccio, C Bianco-Júnior… - Malaria journal, 2015 - Springer
Background The neotropical, non-human primates (NHP) of the genus Saimiri and Aotus are
recommended by the World Health Organization as experimental models for the study of …

A Plasmodium vivax Plasmid DNA- and Adenovirus-Vectored Malaria Vaccine Encoding Blood-Stage Antigens AMA1 and MSP142 in a Prime/Boost Heterologous …

N Obaldia III, MG Stockelman, W Otero… - Clinical and Vaccine …, 2017 - Am Soc Microbiol
Malaria is caused by parasites of the genus Plasmodium, which are transmitted to humans
by the bites of Anopheles mosquitoes. After the elimination of Plasmodium falciparum, it is …