[HTML][HTML] Recent preclinical and clinical progress in liposomal doxorubicin
Doxorubicin (DOX) is a potent anti-cancer agent that has garnered great interest in research
due to its high efficacy despite dose-limiting toxicities. Several strategies have been …
due to its high efficacy despite dose-limiting toxicities. Several strategies have been …
Forcing the antitumor effects of HSPs using a modulated electric field
CA Minnaar, A Szasz - Cells, 2022 - mdpi.com
The role of Heat Shock Proteins (HSPs) is a “double-edged sword” with regards to tumors.
The location and interactions of HSPs determine their pro-or antitumor activity. The present …
The location and interactions of HSPs determine their pro-or antitumor activity. The present …
Heat shock factor 1 inhibition enhances the effects of modulated electro hyperthermia in a triple negative breast cancer mouse model
Female breast cancer is the most diagnosed cancer worldwide. Triple negative breast
cancer (TNBC) is the most aggressive type and there is no existing endocrine or targeted …
cancer (TNBC) is the most aggressive type and there is no existing endocrine or targeted …
[HTML][HTML] Targeting the heat shock response induced by modulated electro-hyperthermia (mEHT) in cancer
Abstract The Heat Shock Response (HSR) is a cellular stress reaction crucial for cell survival
against stressors, including heat, in both healthy and cancer cells. Modulated electro …
against stressors, including heat, in both healthy and cancer cells. Modulated electro …
Enhancing therapeutic efficacy in triple‐negative breast cancer and melanoma: synergistic effects of modulated electro‐hyperthermia (mEHT) with NSAIDs especially …
N Giunashvili, JM Thomas, CA Schvarcz… - Molecular …, 2024 - Wiley Online Library
Triple‐negative breast cancer (TNBC) is a leading cause of cancer mortality and lacks
modern therapy options. Modulated electro‐hyperthermia (mEHT) is an adjuvant therapy …
modern therapy options. Modulated electro‐hyperthermia (mEHT) is an adjuvant therapy …
External basic hyperthermia devices for preclinical studies in small animals
MI Priester, S Curto, GC van Rhoon, TLM Ten Hagen - Cancers, 2021 - mdpi.com
Simple Summary The application of mild hyperthermia can be beneficial for solid tumor
treatment by induction of sublethal effects on a tissue-and cellular level. When designing a …
treatment by induction of sublethal effects on a tissue-and cellular level. When designing a …
Digoxin-Mediated Inhibition of Potential Hypoxia-Related Angiogenic Repair in Modulated Electro-Hyperthermia (mEHT)-Treated Murine Triple-Negative Breast …
SMZ Bokhari, K Aloss, PH Leroy Viana… - ACS Pharmacology & …, 2024 - ACS Publications
Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer type with no
targeted therapy and hence limited treatment options. Modulated electrohyperthermia …
targeted therapy and hence limited treatment options. Modulated electrohyperthermia …
Modulated Electro-Hyperthermia Accelerates Tumor Delivery and Improves Anticancer Activity of Doxorubicin Encapsulated in Lyso-Thermosensitive Liposomes in …
K Aloss, SMZ Bokhari, PH Leroy Viana… - International Journal of …, 2024 - mdpi.com
Modulated electro-hyperthermia (mEHT) is an adjuvant cancer therapy that enables tumor-
selective heating (+ 2.5° C). In this study, we investigated whether mEHT accelerates the …
selective heating (+ 2.5° C). In this study, we investigated whether mEHT accelerates the …
Heterogeneous heat absorption is complementary to radiotherapy
A Szasz - Cancers, 2022 - mdpi.com
Simple Summary This review shows the advantages of heterogeneous heating of selected
malignant cells in harmonic synergy with radiotherapy. The main clinical achievement of this …
malignant cells in harmonic synergy with radiotherapy. The main clinical achievement of this …
A new role of acute phase proteins: Local production is an ancient, general stress-response system of mammalian cells
P Hamar - International Journal of Molecular Sciences, 2022 - mdpi.com
The prevailing general view of acute-phase proteins (APPs) is that they are produced by the
liver in response to the stress of the body as part of a systemic acute-phase response. We …
liver in response to the stress of the body as part of a systemic acute-phase response. We …