Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR)
signaling has crucial roles in a multitude of processes during embryonic development and …

The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …

Skeletal muscles are essential for vital functions such as movement, postural support,
breathing, and thermogenesis. Muscle tissue is largely composed of long, postmitotic …

Adult skeletal muscle in mammals is a stable tissue under normal circumstances but has
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …

The niche is a conserved regulator of stem cell quiescence and function. During ageing,
stem cell function declines. To what extent and by what means age-related changes within …

Tissue injury initiates a complex repair process, which in some organisms can lead to the
complete regeneration of a tissue. In mammals, however, the repair of most organs is …

The family of fibroblast growth factors (FGFs) regulates a plethora of developmental
processes, including brain patterning, branching morphogenesis and limb development …

Chargé, Sophie BP, and Michael A. Rudnicki. Cellular and Molecular Regulation of Muscle
Regeneration. Physiol Rev 84: 209–238, 2004; 10.1152/physrev. 00019.2003.—Under …

Fibroblast growth factors (FGFs) are a family of structurally related polypeptides that are
essential for embryonic development and that function postnatally as homoeostatic factors …

Although members of the fibroblast growth factor (FGF) family and their receptors have well-
established roles in embryogenesis, their contributions to adult physiology remain relatively …