Overview of the 2022 WHO classification of neuroendocrine neoplasms

G Rindi, O Mete, S Uccella, O Basturk, S La Rosa… - Endocrine …, 2022 - Springer
In this review, we detail the changes and the relevant features that are applied to
neuroendocrine neoplasms (NENs) in the 2022 WHO Classification of Endocrine and …

Overview of the 2022 WHO classification of pituitary tumors

SL Asa, O Mete, A Perry, RY Osamura - Endocrine pathology, 2022 - Springer
This review summarizes the changes in the 5th Edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the pituitary gland. The new …

Update from the 5th edition of the world health organization classification of head and neck tumors: overview of the 2022 WHO classification of head and neck …

O Mete, BM Wenig - Head and neck pathology, 2022 - Springer
This review article provides a brief overview of the new WHO classification by adopting a
question–answer model to highlight the spectrum of head and neck neuroendocrine …

Diagnostic, prognostic, and predictive role of Ki67 proliferative index in neuroendocrine and endocrine neoplasms: past, present, and future

S La Rosa - Endocrine Pathology, 2023 - Springer
The introduction of Ki67 immunohistochemistry in the work-up of neuroendocrine neoplasms
(NENs) has opened a new approach for their diagnosis and prognostic evaluation. Since the …

Overview of the 2022 WHO classification of pituitary adenomas/pituitary neuroendocrine tumors: clinical practices, controversies, and perspectives

X Wan, J Chen, J Wang, Y Liu, K Shu, T Lei - Current Medical Science, 2022 - Springer
The latest edition of the WHO classification of the central nervous system was published in
2021. This review summarizes the major revisions to the classification of anterior pituitary …

The complex histopathological and immunohistochemical spectrum of neuroendocrine tumors—an overview of the latest classifications

AA Gheorghișan-Gălățeanu, A Ilieșiu… - International Journal of …, 2023 - mdpi.com
Neuroendocrine neoplasms (NENs) originate from the neuroendocrine cell system, which
may either take the shape of organoid cell aggregations or be composed of dispersed cells …

The Role of Activation of PI3K/AKT/mTOR and RAF/MEK/ERK Pathways in Aggressive Pituitary Adenomas—New Potential Therapeutic Approach—A Systematic …

A Derwich, M Sykutera, B Bromińska, B Rubiś… - International Journal of …, 2023 - mdpi.com
Pituitary tumors (PT) are mostly benign, although occasionally they demonstrate aggressive
behavior, invasion of surrounding tissues, rapid growth, resistance to conventional …

Multilineage pituitary neuroendocrine tumors (PitNETs) expressing PIT1 and SF1

SL Asa, O Mete, ND Riddle, A Perry - Endocrine Pathology, 2023 - Springer
PitNETs are usually restricted in their cytodifferentiation to only one of 3 lineages dictated by
expression of the pituitary transcription factors (TFs) PIT1, TPIT, or SF1. Tumors that show …

[HTML][HTML] From emergence to endemicity: a comprehensive review of COVID-19

R Naik, S Avula, SK Palleti, J Gummadi… - Cureus, 2023 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), later renamed coronavirus
disease 2019 (COVID-19), was first identified in Wuhan, China, in early December 2019 …

PD-L1 Expression in Pituitary Neuroendocrine Tumors/Pituitary Adenomas

G Cossu, S La Rosa, JP Brouland, N Pitteloud, E Harel… - Cancers, 2023 - mdpi.com
Simple Summary The biological behavior of Pituitary Neuroendocrine Tumors (PitNET)
remains unclear. Many efforts have been performed in order to clarify this point. The …