Feelings of hunger and satiety are the key determinants for maintaining the life of humans
and animals. Disturbed appetite control may disrupt the metabolic health of the host and …

The present paper considers recent progress in our understanding of the afferent/ascending
neural pathways and neural circuits of interoception. Of particular note is the extensive role …

We review recent work on the functions of interoceptive processing, by which the nervous
system anticipates, senses, and integrates signals originating from the body. We focus on …

During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

The theory of constructed emotion is a systems neuroscience approach to understanding the
nature of emotion. It is also a general theoretical framework to guide hypothesis generation …

Survival is a fundamental physiological drive, and neural circuits have evolved to prioritize
actions that meet the energy demands of the body. This fine-tuning of goal-directed actions …

Only recently have more specific circuit-probing techniques become available to inform
previous reports implicating the rodent hippocampus in orexigenic appetitive processing …

This paper reviews evidence demonstrating a bidirectional relationship between memory
and eating in humans and rodents. In humans, amnesia is associated with impaired …

Vagal afferent neuron (VAN) signaling sends information from the gut to the brain and is
fundamental in the control of feeding behavior and metabolism [1]. Recent findings reveal …

The peripheral peptide hormone ghrelin is a powerful stimulator of food intake, which leads
to body weight gain and adiposity in both rodents and humans. The hormone, thus …