The cell biology of synapse formation
TC Südhof - Journal of Cell Biology, 2021 - rupress.org
In a neural circuit, synapses transfer information rapidly between neurons and transform this
information during transfer. The diverse computational properties of synapses are shaped by …
information during transfer. The diverse computational properties of synapses are shaped by …
Towards an understanding of synapse formation
TC Südhof - Neuron, 2018 - cell.com
Synapses are intercellular junctions specialized for fast, point-to-point information transfer
from a presynaptic neuron to a postsynaptic cell. At a synapse, a presynaptic terminal …
from a presynaptic neuron to a postsynaptic cell. At a synapse, a presynaptic terminal …
Synaptic neurexin complexes: a molecular code for the logic of neural circuits
TC Südhof - Cell, 2017 - cell.com
Synapses are specialized junctions between neurons in brain that transmit and compute
information, thereby connecting neurons into millions of overlapping and interdigitated …
information, thereby connecting neurons into millions of overlapping and interdigitated …
Alternative splicing of latrophilin-3 controls synapse formation
The assembly and specification of synapses in the brain is incompletely understood,–.
Latrophilin-3 (encoded by Adgrl3, also known as Lphn3)—a postsynaptic adhesion G …
Latrophilin-3 (encoded by Adgrl3, also known as Lphn3)—a postsynaptic adhesion G …
Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins
INTRODUCTION In the brain, synaptic connections form neuronal communication networks,
thereby constructing neural circuits. Synaptic connections are exquisitely specific and …
thereby constructing neural circuits. Synaptic connections are exquisitely specific and …
Alternative splicing of presynaptic neurexins differentially controls postsynaptic NMDA and AMPA receptor responses
J Dai, J Aoto, TC Südhof - Neuron, 2019 - cell.com
AMPA-and NMDA-type glutamate receptors mediate distinct postsynaptic signals that differ
characteristically among synapses. How postsynaptic AMPA-and NMDA-receptor levels are …
characteristically among synapses. How postsynaptic AMPA-and NMDA-receptor levels are …
Adhesion G protein-coupled receptors: structure, signaling, physiology, and pathophysiology
T Lala, RA Hall - Physiological Reviews, 2022 - journals.physiology.org
Adhesion G protein-coupled receptors: structure, signaling, physiology, and
pathophysiology Page 1 REVIEW ARTICLE ADHESION G PROTEIN-COUPLED …
pathophysiology Page 1 REVIEW ARTICLE ADHESION G PROTEIN-COUPLED …
Structural basis for teneurin function in circuit-wiring: a toxin motif at the synapse
Teneurins (TENs) are cell-surface adhesion proteins with critical roles in tissue development
and axon guidance. Here, we report the 3.1-Å cryoelectron microscopy structure of the …
and axon guidance. Here, we report the 3.1-Å cryoelectron microscopy structure of the …
Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands
Extensive studies concluded that homophilic interactions between pre-and postsynaptic
teneurins, evolutionarily conserved cell-adhesion molecules, encode the specificity of …
teneurins, evolutionarily conserved cell-adhesion molecules, encode the specificity of …
Latrophilin GPCR signaling mediates synapse formation
R Sando, TC Südhof - Elife, 2021 - elifesciences.org
Neural circuit assembly in the brain requires precise establishment of synaptic connections,
but the mechanisms of synapse assembly remain incompletely understood. Latrophilins are …
but the mechanisms of synapse assembly remain incompletely understood. Latrophilins are …