Viruses and autoimmunity: a review on the potential interaction and molecular mechanisms

MK Smatti, FS Cyprian, GK Nasrallah, AA Al Thani… - Viruses, 2019 - mdpi.com
For a long time, viruses have been shown to modify the clinical picture of several
autoimmune diseases, including type 1 diabetes (T1D), systemic lupus erythematosus …

Epstein–Barr virus: more than 50 years old and still providing surprises

LS Young, LF Yap, PG Murray - Nature reviews cancer, 2016 - nature.com
It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus, was
discovered. EBV has subsequently been found to be associated with a diverse range of …

Epstein–Barr virus epidemiology, serology, and genetic variability of LMP-1 oncogene among healthy population: an update

MK Smatti, DW Al-Sadeq, NH Ali, G Pintus… - Frontiers in …, 2018 - frontiersin.org
The Epstein–Barr virus (EBV) is a DNA lymphotropic herpesvirus and the causative agent of
infectious mononucleosis. EBV is highly prevalent since it affects more than 90% of …

Current perspectives on nasopharyngeal carcinoma

HM Lee, KS Okuda, FE González, V Patel - … advances in cell models for the …, 2019 - Springer
Abstract Of the~ 129,079 new cases of nasopharyngeal carcinoma (NPC) and 72,987
associated deaths estimated for 2018, the majority will be geographically localized to South …

[HTML][HTML] Epstein-Barr virus and nasopharyngeal carcinoma

LS Young, CW Dawson - Chinese journal of cancer, 2014 - ncbi.nlm.nih.gov
Since its discovery 50 years ago, Epstein-Barr virus (EBV) has been linked to the
development of cancers originating from both lymphoid and epithelial cells. Approximately …

Progress and problems in understanding and managing primary Epstein-Barr virus infections

OA Odumade, KA Hogquist… - Clinical microbiology …, 2011 - Am Soc Microbiol
Epstein-Barr virus (EBV) is a gammaherpesvirus that infects a large fraction of the human
population. Primary infection is often asymptomatic but results in lifelong infection, which is …

Epstein-Barr virus and cancer

MP Thompson, R Kurzrock - Clinical cancer research, 2004 - AACR
EBV was the first human virus to be directly implicated in carcinogenesis. It infects> 90% of
the world's population. Although most humans coexist with the virus without serious …

Genome diversity of Epstein-Barr virus from multiple tumor types and normal infection

AL Palser, NE Grayson, RE White, C Corton… - Journal of …, 2015 - Am Soc Microbiol
Epstein-Barr virus (EBV) infects most of the world's population and is causally associated
with several human cancers, but little is known about how EBV genetic variation might …

Epstein-Barr virus types 1 and 2 differ in their EBNA-3A, EBNA-3B, and EBNA-3C genes

J Sample, L Young, B Martin, T Chatman… - Journal of …, 1990 - Am Soc Microbiol
The two Epstein-Barr virus (EBV) types, EBV-1 and EBV-2, are known to differ in their EBNA-
2 genes, which are 64 and 53% identical in their nucleotide and predicted amino acid …

Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation.

JI Cohen, F Wang, J Mannick… - Proceedings of the …, 1989 - National Acad Sciences
Epstein-Barr virus (EBV) efficiently transforms B lymphocytes to perpetual proliferation. The
EBV laboratory strain P3HR-1 is transformation-incompetent and lacks a DNA segment that …