Pathology and mechanisms of cochlear aging

EM Keithley - Journal of Neuroscience Research, 2020 - Wiley Online Library
Presbycusis, or age‐related hearing loss (ARHL), occurs in most mammals with variations in
the age of onset, rate of decline, and magnitude of degeneration in the central nervous …

The combined effects of occupational exposure to noise and other risk factors− a systematic review

R Golmohammadi, E Darvishi - Noise and Health, 2019 - journals.lww.com
Purpose: Noise-induced health effects exacerbate by many other risk factors. This
systematic review aims at shedding light on the combined effects of co-exposure to …

Systems genetics approaches for understanding complex traits with relevance for human disease

H Allayee, CR Farber, MM Seldin, EG Williams… - Elife, 2023 - elifesciences.org
Quantitative traits are often complex because of the contribution of many loci, with further
complexity added by environmental factors. In medical research, systems genetics is a …

Age-related hearing loss and its potential drug candidates: a systematic review

S Hu, Q Sun, F Xu, N Jiang, J Gao - Chinese Medicine, 2023 - Springer
Background Age-related hearing loss (ARHL) is one of the main illnesses afflicting the aged
population and has a significant negative impact on society, economy, and health. However …

The potential of integrating human and mouse discovery platforms to advance our understanding of cardiometabolic diseases

AW Jurrjens, MM Seldin, C Giles, PJ Meikle, BG Drew… - Elife, 2023 - elifesciences.org
Cardiometabolic diseases encompass a range of interrelated conditions that arise from
underlying metabolic perturbations precipitated by genetic, environmental, and lifestyle …

Effects of man-made sound on terrestrial mammals

H Slabbekoorn, JA McGee, EJ Walsh - Effects of anthropogenic noise on …, 2018 - Springer
Terrestrial mammals are found in all types of natural habitat, and they are also maintained in
large numbers in captivity. Much of what is known about the anatomy and physiology of the …

[HTML][HTML] The use of nonhuman primates in studies of noise injury and treatment

JA Burton, MD Valero, TA Hackett… - The Journal of the …, 2019 - pubs.aip.org
Exposure to prolonged or high intensity noise increases the risk for permanent hearing
impairment. Over several decades, researchers characterized the nature of harmful noise …

Loss of Myh14 increases susceptibility to noise‐induced hearing loss in CBA/CaJ mice

X Fu, L Zhang, Y Jin, X Sun, A Zhang, Z Wen… - Neural …, 2016 - Wiley Online Library
MYH14 is a member of the myosin family, which has been implicated in many motile
processes such as ion‐channel gating, organelle translocation, and the cytoskeleton …

Noise damage accelerates auditory aging and tinnitus: a Canadian population-based study

Z Jafari, T Copps, G Hole, BE Kolb… - Otology & …, 2020 - journals.lww.com
Objective: Age-related hearing loss (ARHL) is the third most challenging disability in older
adults. Noise is a known modifiable risk factor of ARHL, which can drive adverse health …

Genetics of noise-induced hearing loss in the mouse model

S Early, E Du, E Boussaty, R Friedman - Hearing Research, 2022 - Elsevier
Hearing loss is the most common sensory deficit worldwide, with the majority of preventable
injury attributed to noise-induced hearing loss (NIHL). Highly conserved cochlear genetics …