Modifications of lean mass are a frequent critical determinant in the pathophysiology and
progression of heart failure (HF). Sarcopenia may be considered one of the most important …

Sarcopenia is an age-related geriatric syndrome that is characterized by a progressive loss
of muscle mass, strength and function. Chronic heart failure (CHF), the final stage of various …

Context. The exact relationship between the bed rest-induced loss of skeletal muscle and
reductions in muscle strength and physical performance in the older individuals is still …

Aging is accompanied by involuntary loss of skeletal muscle mass, strength and function,
called sarcopenia. The mechanisms underlying the development of sarcopenia are not …

This investigation aimed to compare the response of young and older adult men to bed rest
(BR) and subsequent rehabilitation (R). Sixteen older (OM, age 55-65 yr) and seven young …

Prolonged bed rest and lifelong physical inactivity cause deleterious effects to multiple
physiological systems that appear to hasten aging processes. Many such changes are …

Background: Maintaining skeletal muscle mass and function in aging is crucial for
preserving the quality of life and health. An experimental bed rest (BR) protocol is a suitable …

Abstract Purpose of Review Sarcopenia and frailty are common in patients with heart failure
(HF) and are strongly associated with prognosis. This review aims to examine promising …

Background Older adults exposed to periods of inactivity during hospitalization, illness, or
injury lose muscle mass and strength. This, in turn, predisposes poor recovery of physical …

The aim of this systematic review and meta-analysis [International Prospective Register of
Systematic Reviews (PROSPERO) CRD42017055619] was to assess the effects of strict …