Classic psychedelics, such as LSD, psilocybin, and the DMT-containing beverage
ayahuasca, show some potential to treat depression, anxiety, and addiction. Importantly …

This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

The emerging therapeutic efficacy of ketamine and classical psychedelics for depression
has inspired tremendous interest in the underlying neurobiological mechanisms. We review …

Ketamine has emerged as a transformative and mechanistically novel pharmacotherapy for
depression. Its rapid onset of action, efficacy for treatment-resistant symptoms, and …

Psychedelics have inspired new hope for treating brain disorders, as they seem to be unlike
any treatments currently available. Not only do they produce sustained therapeutic effects …

The ability to behave in ways that benefit other individuals' well-being is among the most
celebrated human characteristics crucial for social cohesiveness. Across mammalian …

In addition to producing profound subjective effects following acute administration,
psychedelic compounds can induce beneficial behavioral changes relevant to the treatment …

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by impairments in social interaction and communication along with repetitive stereotypic …

Psychedelic compounds have displayed antidepressant potential in both humans and
rodents. Despite their promise, psychedelics can induce undesired effects that pose safety …

Psilocybin is a psychedelic with therapeutic potential. While there is growing evidence that
psilocybin exerts its beneficial effects through enhancing neural plasticity, the exact brain …