The fragments that derive from transfer RNAs (tRNAs) are an emerging category of
regulatory RNAs. Known as tRFs, these fragments were reported for the first time only a …

The partitioning of genetic material between the nucleus and cytoplasmic (mitochondrial and
plastid) genomes within eukaryotic cells necessitates coordinated integration between these …

tRNA fragments (tRFs) and tRNA halves have been implicated in various cellular processes,
including gene silencing, translation, stress granule assembly, cell differentiation …

RNA can fold back on itself to adopt a wide range of structures. These range from relatively
simple hairpins to intricate 3D folds and can be accompanied by regulatory interactions with …

Although mitochondrial contributions to cancer have been recognised for approximately a
century, given that mitochondrial DNA (mtDNA) is dwarfed by the size of the nuclear genome …

Translation is a crucial step in gene expression and plays a vital role in regulating various
aspects of plant development and environmental responses. It is a dynamic and complex …

In the absence of extensive transcription control mechanisms the pathogenic parasite
Trypanosoma brucei crucially depends on translation regulation to orchestrate gene …

The advent of RNA-sequencing (RNA-Seq) technologies has markedly improved our
knowledge and expanded the compendium of small non-coding RNAs, most of which derive …

Transfer RNA-derived small RNAs (tsRNAs) are an emerging class of small RNAs, yet their
regulatory roles have not been well understood. Here we studied the molecular mechanisms …

RNA fragments deriving from tRNAs (tRFs) exist in all branches of life and the repertoire of
their biological functions regularly increases. Paradoxically, their biogenesis remains …