Biofilm-camouflaged Prussian blue synergistic mitochondrial mass enhancement for Alzheimer's disease based on Cu2+ chelation and photothermal therapy
L Li, Y Xiong, Y Zhang, Y Yan, R Zhao, F Yang… - Journal of Controlled …, 2024 - Elsevier
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases
characterized by cognitive and memory impairment. Metal ion imbalance and Mitochondrial …
characterized by cognitive and memory impairment. Metal ion imbalance and Mitochondrial …
Gallic acid ameliorates LPS-induced memory decline by modulating NF-κB, TNF-α, and Caspase 3 gene expression and attenuating oxidative stress and neuronal …
Neuroinflammation and apoptosis play critical roles in the pathogenesis of Alzheimer's
disease (AD), which is responsible for most cases of dementia in the elderly people. Gallic …
disease (AD), which is responsible for most cases of dementia in the elderly people. Gallic …
miR-34a/TAN1/CREB Axis Engages in Alleviating Oligodendrocyte Trophic Factor-Induced Myelin Repair Function and Astrocyte-Dependent Neuroinflammation in …
Y Liu, XK Meng, W Shao, Y Liu, C Tang, S Deng… - Neurochemical …, 2024 - Springer
Reduced myelin stability observed in the early stages of Alzheimer's disease leads to spatial
learning and memory impairment. Exercise has been shown to protect nerves, reduce the …
learning and memory impairment. Exercise has been shown to protect nerves, reduce the …
Development, optimization, and evaluation of Empagliflozin nanoemulsion for the management of neuroinflammation associated Alzheimer's disease
NA Alhakamy, EA Aljehani, AB Abdel-Naim… - Journal of Drug Delivery …, 2024 - Elsevier
Alzheimer's disease (AD) is one of the most pervasive and progressive neurodegenerative
disorders. Recently, empagliflozin (EMPA) has been reported as a potent anti-inflammatory …
disorders. Recently, empagliflozin (EMPA) has been reported as a potent anti-inflammatory …
Central innate immunization induces tolerance against post-traumatic stress disorder-like behavior and neuroinflammatory responses in male mice
M Ye, H Zhu, X Lu, R Yang, H Wang, J Peng… - Brain, Behavior, and …, 2024 - Elsevier
Post-traumatic stress disorder (PTSD) is a severe psychiatric disorder associated with
abnormally elevated neuroinflammatory responses. Suppression of neuroinflammation is …
abnormally elevated neuroinflammatory responses. Suppression of neuroinflammation is …
Microglial priming by IFN‐γ involves STAT1‐mediated activation of the NLRP3 inflammasome
H He, X Zhang, H He, G Xu, L Li, C Yang… - CNS Neuroscience …, 2024 - Wiley Online Library
Background Inflammatory and immune responses in the brain that contribute to various
neuropsychiatric disorders may begin as microglial “priming”. Interferon (IFN)‐γ is known to …
neuropsychiatric disorders may begin as microglial “priming”. Interferon (IFN)‐γ is known to …
[HTML][HTML] Dynamic microglia alterations associate with hippocampal network impairments: A turning point in amyloid pathology progression
G Pizzirusso, E Preka, J Goikolea… - Brain, Behavior, and …, 2024 - Elsevier
Alzheimer's disease is a progressive neurological disorder causing memory loss and
cognitive decline. The underlying causes of cognitive deterioration and neurodegeneration …
cognitive decline. The underlying causes of cognitive deterioration and neurodegeneration …
CCR3 knockdown attenuates prolonged underwater operations-induced cognitive impairment via alleviating microglia-mediated neuroinflammation
H Zhao, K Liang, Z Yu, Y Wen, X Yu, J Xin, T Zhang… - Iscience, 2024 - cell.com
Maintaining cognitive integrity is crucial during underwater operations, which can
significantly impact work performance and risk severe accidents. However, the cognitive …
significantly impact work performance and risk severe accidents. However, the cognitive …
[HTML][HTML] Hyperbaric oxygen preconditioning rescues prolonged underwater exercise-induced hippocampal dysfunction by regulating microglia activation and …
H Zhao, K Liang, Z Yu, Y Wen, J Shi, T Zhang… - Neuroscience …, 2024 - Elsevier
Underwater exercise is becoming increasingly prevalent, during which brain function is
necessary but is also at risk. However, no study has explored how prolonged exercise affect …
necessary but is also at risk. However, no study has explored how prolonged exercise affect …
Association of microglia loss with hippocampal network impairments as a turning point in the amyloid pathology progression
G Pizzirusso, E Preka, J Goikolea, C Aguilar-Ruiz… - bioRxiv, 2024 - biorxiv.org
Alzheimer's disease is a progressive neurological disorder causing memory loss and
cognitive decline. The underlying causes of cognitive deterioration and neurodegeneration …
cognitive decline. The underlying causes of cognitive deterioration and neurodegeneration …