Autophagy exacerbates muscle wasting in cancer cachexia and impairs mitochondrial function
F Penna, R Ballarò, P Martinez-Cristobal, D Sala… - Journal of molecular …, 2019 - Elsevier
Cancer cachexia is a multifactorial syndrome characterized by anorexia, weight loss and
muscle wasting that impairs patients' quality of life and survival. Aim of this work was to …
muscle wasting that impairs patients' quality of life and survival. Aim of this work was to …
Oxidative stress induces downregulation of TP53INP2 and suppresses osteogenic differentiation of BMSCs during osteoporosis through the autophagy degradation …
Y Yang, Y Sun, W Mao, H Zhang, B Ni… - Free Radical Biology and …, 2021 - Elsevier
Oxidative stress plays an important role in the pathogenesis of osteoporosis and impaired
bone formation. However, the mechanisms behind which oxidative stress represses bone …
bone formation. However, the mechanisms behind which oxidative stress represses bone …
Meta-signature LncRNAs serve as novel biomarkers for colorectal cancer: integrated bioinformatics analysis, experimental validation and diagnostic evaluation
M Dai, X Chen, S Mo, J Li, Z Huang, S Huang, J Xu… - Scientific reports, 2017 - nature.com
The aim of this study is to explore the differentially expressed lncRNAs, which may have
potential biological function and diagnostic value in colorectal cancer (CRC). Through …
potential biological function and diagnostic value in colorectal cancer (CRC). Through …
Construction of the first high-density genetic linkage map and QTL mapping for growth traits in black seabream (Acanthopagrus schlegelii)
C Jia, Q Meng, S Chen, R Sun, D Xu, F Zhu, B Gao… - Aquaculture, 2025 - Elsevier
Quantitative trait loci (QTL) mapping is a powerful approach for marker-assisted selection
(MAS) in improving growth-related traits, with the construction of high-density genetic …
(MAS) in improving growth-related traits, with the construction of high-density genetic …
MicroRNA‐34a: a key regulator in the hallmarks of renal cell carcinoma
EA Toraih, AT Ibrahiem, MS Fawzy… - Oxidative Medicine …, 2017 - Wiley Online Library
Renal cell carcinoma (RCC) incidence has increased over the past two decades. Recent
studies reported microRNAs as promising biomarkers for early cancer detection, accurate …
studies reported microRNAs as promising biomarkers for early cancer detection, accurate …
TP53INP2 Contributes to TGF-β2-Induced Autophagy during the Epithelial–Mesenchymal Transition in Posterior Capsular Opacification Development
Y Cui, H Yang, S Shi, X Ping, S Zheng, X Tang, X Yu… - Cells, 2022 - mdpi.com
Background: Posterior capsule opacification (PCO) is the most common complication after
cataract surgery, in which increased levels of transforming growth factor-beta 2 (TGF-β2) …
cataract surgery, in which increased levels of transforming growth factor-beta 2 (TGF-β2) …
Integrated bioinformatics, network pharmacology, and artificial intelligence to predict the mechanism of celastrol against muscle atrophy caused by colorectal cancer
M Wu, Y Zhang - Frontiers in Genetics, 2022 - frontiersin.org
Muscle atrophy due to colorectal cancer severely reduces the quality of life and survival time
of patients. However, the underlying causative mechanisms and therapeutic agents are not …
of patients. However, the underlying causative mechanisms and therapeutic agents are not …
HIF-3α Facilitates the Proliferation and Migration in Pancreatic Cancer by Inhibiting Autophagy Through Downregulating TP53INP2
X Zhou, Y Ling, L Huang, F Yang, Y Zhang… - Cell Biochemistry and …, 2024 - Springer
Pancreatic cancer is a highly aggressive malignant tumor, often diagnosed late, leading to a
poor prognosis and extremely high mortality rates. In recent years, the role of cellular …
poor prognosis and extremely high mortality rates. In recent years, the role of cellular …
The axonal transcript Tp53inp2 mediates the development of the sympathetic nervous system
H Crerar - 2018 - discovery.ucl.ac.uk
Nerve Growth Factor (NGF) is a neurotrophin essential for the survival of sympathetic and
sensory neurons. Localisation of mRNA in axons of NGF-dependent neurons supports …
sensory neurons. Localisation of mRNA in axons of NGF-dependent neurons supports …
[PDF][PDF] Research Article MicroRNA-34a: A Key Regulator in the Hallmarks of Renal Cell Carcinoma
EA Toraih, AT Ibrahiem, MS Fawzy, MH Hussein… - 2017 - academia.edu
Renal cell carcinoma (RCC) incidence has increased over the past two decades. Recent
studies reported microRNAs as promising biomarkers for early cancer detection, accurate …
studies reported microRNAs as promising biomarkers for early cancer detection, accurate …