Nanocaged platforms: modification, drug delivery and nanotoxicity. Opening synthetic cages to release the tiger
Nanocages (NCs) have emerged as a new class of drug-carriers, with a wide range of
possibilities in multi-modality medical treatments and theranostics. Nanocages can …
possibilities in multi-modality medical treatments and theranostics. Nanocages can …
Role of endothelial nitric oxide synthase in diabetic nephropathy: lessons from diabetic eNOS knockout mice
T Takahashi, RC Harris - Journal of diabetes research, 2014 - Wiley Online Library
Diabetic nephropathy (DN) is the leading cause of end‐stage renal disease in many
countries. The animal models that recapitulate human DN undoubtedly facilitate our …
countries. The animal models that recapitulate human DN undoubtedly facilitate our …
Predicted consequences of diabetes and SGLT inhibition on transport and oxygen consumption along a rat nephron
Diabetes increases the reabsorption of Na+ (TNa) and glucose via the sodium-glucose
cotransporter SGLT2 in the early proximal tubule (S1-S2 segments) of the renal cortex …
cotransporter SGLT2 in the early proximal tubule (S1-S2 segments) of the renal cortex …
Dual-modality and Noninvasive Diagnostic of MNP–PEG–Mn Nanoprobe for Renal Fibrosis Based on Photoacoustic and Magnetic Resonance Imaging
Y Yang, T Li, W Jing, Z Yan, X Li, W Fu… - ACS Applied Materials …, 2023 - ACS Publications
To date, imaging-guided multimodality therapy is important to improve the accuracy of the
diagnosis of renal fibrosis, and nanoplatforms for imaging-guided multimodality diagnosis …
diagnosis of renal fibrosis, and nanoplatforms for imaging-guided multimodality diagnosis …
How do kidneys adapt to a deficit or loss in nephron number?
A deficit or loss in the number of nephrons, the functional unit of the kidney, can induce
compensatory growth and hyperfunction of remaining nephrons. An increase in single …
compensatory growth and hyperfunction of remaining nephrons. An increase in single …
Physiological principles underlying the kidney targeting of renal nanomedicines
Kidney disease affects more than 10% of the global population and is associated with
considerable morbidity and mortality, highlighting a need for new therapeutic options …
considerable morbidity and mortality, highlighting a need for new therapeutic options …
MRI-based glomerular morphology and pathology in whole human kidneys
SC Beeman, LA Cullen-McEwen… - American Journal …, 2014 - journals.physiology.org
Nephron number (N glom) and size (Vglom) are correlated with risk for chronic
cardiovascular and kidney disease and may be predictive of renal allograft viability …
cardiovascular and kidney disease and may be predictive of renal allograft viability …
[HTML][HTML] In-vivo evaluation of molybdenum as bioabsorbable stent candidate
M Sikora-Jasinska, LM Morath, MP Kwesiga… - Bioactive Materials, 2022 - Elsevier
Biodegradable stents have tremendous theoretical potential as an alternative to bare metal
stents and drug-eluting stents for the treatment of obstructive coronary artery disease. Any …
stents and drug-eluting stents for the treatment of obstructive coronary artery disease. Any …
Small blob identification in medical images using regional features from optimum scale
Recent advances in medical imaging technology have greatly enhanced imaging-based
diagnosis which requires computational effective and accurate algorithms to process the …
diagnosis which requires computational effective and accurate algorithms to process the …
[HTML][HTML] Phenotyping by magnetic resonance imaging nondestructively measures glomerular number and volume distribution in mice with and without nephron …
EJ Baldelomar, JR Charlton, SC Beeman, BD Hann… - Kidney international, 2016 - Elsevier
Reduced nephron mass is strongly linked to susceptibility to chronic renal and
cardiovascular diseases. There are currently no tools to identify nephropenia in clinical or …
cardiovascular diseases. There are currently no tools to identify nephropenia in clinical or …